Evidence map›Paper›PMID 24219183›Full record

ArticleJournal of consulting and clinical psychology2014

Anhedonia, depressed mood, and smoking cessation outcome.

Adam M Leventhal, Megan E Piper, Sandra J Japuntich, Timothy B Baker, Jessica W Cook

Open access · greenAbstract read
In one paragraph

Article in Journal of consulting and clinical psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Smoking cessation for improving mental health.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Pooled it
  3. Trial
  4. Behavioral Activation mHealth Application for Smoking Cessation: A Randomized Controlled Pilot Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Trial
  5. Depression Severity Moderates Reward Learning Among Smokers With Current or Past Major Depressive Disorder in a Smoking Cessation Randomized Clinical Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Which Method of Assessing Depression and Anxiety Best Predicts Smoking Cessation: Screening Instruments or Self-Reported Conditions?Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Trial
  11. The effects of mindfulness-based yogic breathing on craving, affect, and smoking behavior.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
    Trial
  12. Trial
  13. Trial
  14. Trial
  15. Is the Effect of Anhedonia on Smoking Cessation Greater for Women Versus Men?Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Trial
  16. Trial
  17. Article
  18. Associations of Trait Psychomotor Restlessness and Agitation With Tobacco Withdrawal Symptoms in a Nonclinical Sample of Adults Who Smoke Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adam M LeventhalDepartment of Preventive Medicine, University of Southern California Keck School of Medicine.
Megan E PiperCenter for Tobacco Research and Intervention, Department of Medicine, University of Wisconsin School of Medicine and Public Health.
Sandra J JapuntichNational Center for PTSD, Veterans Affairs Boston Healthcare System.
Timothy B BakerCenter for Tobacco Research and Intervention, Department of Medicine, University of Wisconsin School of Medicine and Public Health.
Jessica W CookCenter for Tobacco Research and Intervention, Department of Medicine, University of Wisconsin School of Medicine and Public Health.
University of Wisconsin–Madison · USUniversity of Southern California · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Testing Relapse Recovery Intervention ComponentsP01CA180945 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BOLT, DANIEL M · 2014 to 2023
$23.0M
Enhancing the Effectiveness of Varenicline Based Smoking Cessation TreatmentR01HL109031 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B, STEIN, JAMES H · 2011 to 2020
$17.5M
Institutional Clinical and Translational Science Award (UW-Madison)KL2RR025012 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$11.1M
Transforming The Treatment of Tobacco Use in Health Care: Seizing The Potential of the Electronic Health Record to Deliver Comprehensive Chronic Care Treatment for SmokingR35CA197573 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MICHAEL C FIORE · 2015 to 2026
$10.7M
Tobacco Dependence: Treatment and OutcomesP50DA019706 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI JACKSON, THOMAS C · 2004 to 2008
$8.6M
Training in Translational Tobacco ScienceK05CA139871 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B · 2008 to 2012
$850k
Influence of Nicotine on Positive and Negative Affect in Smokers with PTSDK08DA021311 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI COOK, JESSICA MEGAN · 2007 to 2011
$827k
Affective and Genetic Correlates of Amphetamine ResponseK08DA025041 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEVENTHAL, ADAM MATTHEW · 2009 to 2013
$773k
Advancing Tobacco Research by Integrating Systems Science and Mixture ModelsR01CA168676 · NCI · PENNSYLVANIA STATE UNIVERSITY, THE · PI LANZA, STEPHANIE T · 2012 to 2014
$498k
NCATS NIH HHS UL1 TR000427NCI NIH HHS 1K05CA139871NCI NIH HHS K05 CA139871NCI NIH HHS P01 CA180945NCI NIH HHS R01 CA168676NCRR NIH HHS 1KL2RR025012-0NCRR NIH HHS 1UL1RR025011 FROMNCRR NIH HHS KL2 RR025012NCRR NIH HHS UL1 RR025011NHLBI NIH HHS R01 HL109031NIDA NIH HHS K08 DA021311NIDA NIH HHS K08DA021311NIDA NIH HHS K08DA02504NIDA NIH HHS K08 DA025041NIDA NIH HHS P50 DA019706NIDA NIH HHS P50DA019706
6 · The paper itself

Abstract

objectiveAlthough the relation between lifetime depression and smoking cessation outcome has been well studied, the proposition that different symptomatic expressions of depression exert disparate predictive effects on risk of smoking cessation failure has largely gone uninvestigated. This study analyzed the individual contributions of depression's 2 hallmark affective symptoms, anhedonia (i.e., diminished interest in normally enjoyable activities) and depressed mood (i.e., elevated sadness), to the prediction of smoking cessation outcome.

methodParticipants were adult daily smokers (N = 1,469; mean age = 45 years, 58% female, 84% White) enrolled in a smoking cessation treatment study. Lifetime history of anhedonia and depressed mood were classified via structured interview prior to quit day. Seven-day point prevalence smoking abstinence was assessed at 8 weeks and 6 months postquit.

resultsWhen examined separately, both lifetime anhedonia, OR (95% CI) = 1.42 (1.16, 1.73), p = .004, and depressed mood, OR (95% CI) = 1.35 (1.11, 1.63), p = .002, predicted increased odds of relapse. These relations remained after adjusting for covariates, including lifetime depressive disorder, which did not predict outcome. After controlling for the covariation between lifetime anhedonia and depressed mood, anhedonia predicted cessation outcome, OR (95% CI) = 1.31 (1.05, 1.62), p = .02, while depressed mood did not (p = .19). Symptom duration (>2 weeks), treatment, and substance use disorder did not modify relations of lifetime anhedonia and depressed mood with cessation outcome.

conclusionsResults suggest that (1) symptoms of affective disturbance capture depression-relevant risk of cessation failure, which is not adequately demarcated by the lifetime depressive disorder diagnosis, and (2) anhedonia is a more sensitive index of this affective disturbance than depressed mood per se. Clinical attention to anhedonia may facilitate smoking cessation.

Indexed as

AffectAnhedoniaAdultDepressionFemaleHumansMaleMiddle AgedSmoking CessationTobacco Use Disorder

Identifiers

PMID24219183
PMCPMC3934823
OpenAlexW1967300857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.