ReviewJournal of cutaneous pathology2014
Cutaneous metastases as an initial manifestation of visceral well-differentiated neuroendocrine tumor: a report of four cases and a review of literature.
Review in Journal of cutaneous pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- Cutaneous Neuroendocrine Metastases of Visceral Origin Responsive to Surgical Resection and Targeted Radionuclide Therapy.Case reports in dermatological medicine · 2024Article
- Skin manifestations of pancreatic diseases.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2022Review
- Sweat-gland carcinoma with neuroendocrine differentiation (SCAND): a clinicopathologic study of 13 cases with genetic analysis.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022Article
- Primary hepatic carcinoid tumor metastasizing to eyelid: A case report.American journal of ophthalmology case reports · 2019Article
- Rare breast and subcutaneous metastases from pancreatic neuroendocrine tumor: a case report.World journal of surgical oncology · 2019Article
- A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2018Article
- Soft Tissue Primary Neuroendocrine Tumor: A Case Report.The American journal of case reports · 2018Article
- Cutaneous metastasis as an initial presentation of a non-functioning pancreatic neuroendocrine tumor.World journal of gastroenterology · 2015Article
- [Skin metastases seen at the pathology laboratory in Lome, Togo, between 2005 and 2014].The Pan African medical journal · 2015Article
- Neuroendocrine carcinoma of the larynx with subcutaneous and intramuscular metastases: a case report.International journal of clinical and experimental pathology · 2014Article
- Cutaneous Metastasis of Neuroendocrine Carcinoma with Unknown Primary Site: Case Report and Review of the Literature.Case reports in dermatologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Well-differentiated neuroendocrine tumors metastasize to the skin uncommonly, and only 35 cases are reported in the literature. In only five of these patients, cutaneous metastases were the presenting symptom of malignancy; herein, we report four such cases. Two patients were female and two male, aged 50-74 years (mean: 64.5 years), each with a solitary painless, slowly enlarging, non-ulcerated cutaneous nodule of 3-12 months duration (mean: 9 months). The lesions were on the scalp (n = 3) and trunk (n = 1), and ranged in greatest dimension from 0.5 to 2.5 cm. The distinction from other microscopically similar entities, and the interpretation of origination from gastrointestinal, pancreatic or respiratory system primaries, was made clinically, or was based on the morphological features and the immunohistochemical profile. One patient died of the disease progression after 36 months whereas two patients are alive with significant disease progression after 24 and 60 months. Metastatic neuroendocrine tumor should be considered in the differential diagnosis of cutaneous tumors with neuroendocrine morphology even in patients with no known history of visceral malignancy.
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