ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2014
Developments in CD4 and viral load monitoring in resource-limited settings.
Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Point-of-care viral load tests to detect high HIV viral load in people living with HIV/AIDS attending health facilities.The Cochrane database of systematic reviews · 2022Pooled it
- Improved HIV-1 Viral Load Monitoring Capacity Using Pooled Testing With Marker-Assisted Deconvolution.Journal of acquired immune deficiency syndromes (1999) · 2017Pooled it
- Impact of point-of-care CD4 testing on linkage to HIV care: a systematic review.Journal of the International AIDS Society · 2014Pooled it
- Construction of Machine Learning Models to Predict Changes in Immune Function Using Clinical Monitoring Indices in HIV/AIDS Patients After 9.9-Years of Antiretroviral Therapy in Yunnan, China.Frontiers in cellular and infection microbiology · 2022Article
- Determinants of viral load non-suppression among adolescents in Mbale District, Eastern Rural Uganda.AIDS research and therapy · 2021Article
- Is group testing ready for prime-time in disease identification?Statistics in medicine · 2021Article
- Adaptive Viral Load Monitoring Frequency to Facilitate Differentiated Care: A Modeling Study From Rakai, Uganda.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Leaving no one behind: lessons from implementation of policies for universal HIV treatment to universal health coverage.Globalization and health · 2020Article
- Targeting the HIV Epidemic in South Africa: The Need for Testing and Linkage to Care in Emergency Departments.EClinicalMedicine · 2019Article
- Toward Improving Accessibility of Point-of-Care Diagnostic Services for Maternal and Child Health in Low- and Middle-Income Countries.Point of care · 2019Article
- Article
- Performance and usability of Cepheid GeneXpert HIV-1 qualitative and quantitative assay in Kenya.PloS one · 2019Article
- Parasites may exit immunocompromised northern pig-tailed macaques (Zoological research · 2018Article
- Evaluating the utility of provider-recorded clinical status in the medical records of HIV-positive adults in a limited-resource setting.International journal of STD & AIDS · 2017Article
- Point-of-Care Viral Load Testing for Sub-Saharan Africa: Informing a Target Product Profile.Open forum infectious diseases · 2016Article
- CD4 Variability in Malawi: Implications for Use of a CD4 Threshold of 500 Cells/mmOpen forum infectious diseases · 2016Article
- Impact of nurse-delivered community-based CD4 services on facilitating pre-ART care in rural South Africa.BMC health services research · 2016Article
- Availability and Use of HIV Monitoring and Early Infant Diagnosis Technologies in WHO Member States in 2011-2013: Analysis of Annual Surveys at the Facility Level.PLoS medicine · 2016Article
- Effects of unplanned treatment interruptions on HIV treatment failure - results from TAHOD.Tropical medicine & international health : TM & IH · 2016Observational
- Article
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Authors and funding
1 author.
Funding
Abstract
CD4 counts and human immunodeficiency virus (HIV) load testing are essential components of HIV care, and making these tests available in resource-limited settings is critical to the roll-out of HIV treatment globally. Until recently, the evidence supporting the importance of laboratory monitoring in resource-limited settings was lacking, but there is now a consensus emerging that testing should become routine to ensure the longevity of treatment programs. Low-cost, point-of-care testing offers the potential to fill this role as it potentially improves all aspects of HIV care, ranging from the diagnosis and staging of HIV infection in both infants and adults to monitoring for treatment failure once antiretroviral therapy has been initiated. It is imperative for low-cost solutions to become a reality, but it is equally imperative that close scrutiny be given to each new device that hits the market to ensure they perform optimally in all settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.