ReviewEuropean journal of nuclear medicine and molecular imaging2014
Ischaemic memory imaging using metabolic radiopharmaceuticals: overview of clinical settings and ongoing investigations.
Review in European journal of nuclear medicine and molecular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Construction and validation of a diagnostic model for obstructive coronary artery disease in patients with suspected unstable angina pectoris based on restingQuantitative imaging in medicine and surgery · 2026Article
- Cardiovascular imaging in cardio-oncology.Japanese journal of radiology · 2024Review
- Hemodialysis patients have signs of a chronic thrombotic burden.BMC nephrology · 2024Observational
- Cardiac 18F‑FDG uptake and new‑onset rectal cancer.Oncology letters · 2023Article
- Value of restJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Myocardial salvage after ST-segment-elevation myocardial infarction: comparison between prasugrel and clopidogrel in the presence or absence of high-residual platelet reactivity.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Successfully treated eosinophilic granulomatosis with polyangiitis relapse presenting as myocarditis and followed by multimodality imaging.Journal of cardiology cases · 2018Article
- Radiopharmaceutical tracers for cardiac imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Takotsubo cardiomyopathy: FDG myocardial uptake pattern in fasting patients. Comparison of PET/CT, SPECT, and ECHO results.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Comparisons and contrasts in the practice of nuclear cardiology in the United States and Japan.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Accelerated (99m)Tc-sestamibi clearance associated with mitochondrial dysfunction and regional left ventricular dysfunction in reperfused myocardium in patients with acute coronary syndrome.EJNMMI research · 2016Article
- Noninvasive cardiac imaging in suspected acute coronary syndrome.Nature reviews. Cardiology · 2016Review
- Current status of nuclear cardiology in Japan: Ongoing efforts to improve clinical standards and to establish evidence.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Review
- Direct myocardial ischemia imaging: a new cardiovascular nuclear imaging paradigm.Clinical cardiology · 2015Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
"Ischaemic memory" is defined as a prolonged functional and/or biochemical alteration remaining after a particular episode of severe myocardial ischaemia. The biochemical alteration has been reported as metabolic stunning. Metabolic imaging has been used to detect the footprint left by previous ischaemic episodes evident due to delayed recovery of myocardial metabolism (persistent dominant glucose utilization with suppression of fatty acid oxidation). β-Methyl-p-[(123)I]iodophenylpentadecanoic acid (BMIPP) is a single-photon emission computed tomography (SPECT) radiotracer widely used for metabolic imaging in clinical settings in Japan. In patients with suspected coronary artery disease but no previous myocardial infarction, BMIPP has shown acceptable diagnostic accuracy. In particular, BMIPP plays an important role in the identification of prior ischaemic insult in patients arriving at emergency departments with acute chest pain syndrome. Recent data also show the usefulness of (123)I-BMIPP SPECT for predicting cardiovascular events in patients undergoing haemodialysis. Similarly, SPECT or PET imaging with (18)F-FDG injected during peak exercise or after exercise under fasting conditions shows an increase in FDG uptake in postischaemic areas. This article will overview the roles of ischaemic memory imaging both under established indications and in ongoing investigations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.