ArticleCardiovascular journal of Africa2013
Association of homocysteinaemia with hyperglycaemia, dyslipidaemia, hypertension and obesity.
Article in Cardiovascular journal of Africa, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 25 citations in OpenAlex.
- Association of homocysteine and uric acid with type 2 diabetes mellitus: a case-control study.Scientific reports · 2025Article
- Association between body fat composition and hyperhomocysteinemia in the analysis of the baseline data of the Northwest China Natural Population Cohort: Ningxia Project (CNC-NX).Journal of clinical hypertension (Greenwich, Conn.) · 2023Observational
- Activation of arginase II by asymmetric dimethylarginine and homocysteine in hypertensive rats induced by hypoxia: a new model of nitric oxide synthesis regulation in hypertensive processes?Hypertension research : official journal of the Japanese Society of Hypertension · 2021Review
- Association between serum homocysteine level and cognitive function in middle-aged type 2 diabetes mellitus patients.PloS one · 2019Article
- Interactions of homocysteine and conventional predisposing factors on hypertension in Chinese adults.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Toll-like receptor 4 mediates vascular remodeling in hyperhomocysteinemia.Molecular and cellular biochemistry · 2017Review
- Effects of improved fat meat products consumption on emergent cardiovascular disease markers of male volunteers at cardiovascular risk.Journal of physiology and biochemistry · 2016Article
- High renal resistive index in hypertensive patients is also associated with serum homocysteine level.Clinical and experimental nephrology · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimHyperhomocysteinaemia and the metabolic syndrome are associated with increased cardiovascular risk. We investigated whether there is a link between the metabolic syndrome or its components and homocysteine levels in a population without cardiovascular disease.
methodsFrom the population sample of 382 participants (286 females and 96 males) we isolated those reflecting the metabolic syndrome and determined their homocysteine levels. We then evaluated the association of homocysteine with hyperglycaemia, hypertriglyceridaemia, hypercholesterolaemia, hypertension and obesity, using a significance level of p = 0.05. Enzymatic methods were used for all biochemical parameters.
resultsWe found the statistical relationship between homocysteine and the metabolic syndrome as follows: hyperglycaemia (p = 0.175), hypertriglyceridaemia (p = 0.442), hypercholesterolaemia (p = 0.480), obesity (p = 0.080); and hypertension: systolic pressure (p = 0.002) and diastolic pressure (p = 0.033).
conclusionWe found no statistically significant association between baseline plasma homocysteine levels and the metabolic syndrome, except for hypertension.
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