Evidence map›Paper›PMID 24216056›Full record

ArticleJournal of neurodevelopmental disorders2013

Examining associations between anxiety and cortisol in high functioning male children with autism.

David M Simon, Blythe A Corbett

Abstract read
In one paragraph

Article in Journal of neurodevelopmental disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
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  7. Sensory Processing and Anxiety: Within and Beyond the Autism Spectrum.Current topics in behavioral neurosciences · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. The impact of COVID-19 on stress, anxiety, and coping in youth with and without autism and their parents.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  12. Article
  13. Article
  14. Camouflaging in Autism: Examining Sex-Based and Compensatory Models in Social Cognition and Communication.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David M Simon
Blythe A CorbettDepartment of Psychiatry, Vanderbilt University, 230 Appleton Way, 37203 Nashville, TN, USA. blythe.corbett@vanderbilt.edu.

Funding

Psychobiological investigation of the socioemotional functioning in autismR01MH085717 · NIMH · VANDERBILT UNIVERSITY · PI CORBETT, BLYTHE ANNE · 2010 to 2014
$1.7M
NIMH NIH HHS R01 MH085717
6 · The paper itself

Abstract

backgroundAutism spectrum disorder (ASD) is characterized by deficits in communication and social ability, as well as restricted interests and repetitive behavior. Anxiety is a persistent anticipation or apprehension about one or more situations to which a person is exposed, and affects many people, including children with ASD. Stress, by contrast, is a response to situations that are threatening, uncontrollable, or unexpected. Indices of anxiety are often measured through informants, with parents and teachers serving as the primary sources of reported anxiety in children. However, self-report measures exist, allowing current (state) and persistent (trait) anxiety to be assessed. The current study was designed to evaluate whether children with autism could identify their own levels of anxiety and the degree to which these levels were associated with symptom profile and physiological arousal.

methodsSelf-reported state and trait anxiety were collected during exposure to different stress paradigms for 40 children (21 typically developing, 19 with autistic disorder) and compared to parent reported social ability (Social Responsiveness Scale) and stress responsivity (cortisol).

resultsSignificant differences were found between typically developing and children with autism for both state and trait anxiety across all conditions. Associations were identified between severity of parent-reported social impairment and both types of self-report anxiety. No relationship was found between stress (salivary cortisol) and anxiety in children with autism.

conclusionsChildren with autism are able to consistently report their persistent level of anxiety symptoms in stressful situations of benign character. Therefore, the inclusion of such measures may be useful in identifying and tracking symptoms in children with autism under appropriate circumstances.

Identifiers

PMID24216056
PMCPMC3827503

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.