Evidence map›Paper›PMID 24215379›Full record

ReviewInfluenza and other respiratory viruses2013

Viral-bacterial interactions-therapeutic implications.

Jane C Deng

Open access · bronzeAbstract readReview
In one paragraph

Review in Influenza and other respiratory viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. COVID-19 and Influenza Deaths in Australian Children 2018-2023: A National Case Analysis.Journal of the Pediatric Infectious Diseases Society · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. [Bacteriologic profile and drug resistance in children with respiratory infection from 2016 to 2018].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019
    Article
  14. Integrative Physiology of Pneumonia.Physiological reviews · 2018
    Review
  15. Article
  16. Antivirals against animal viruses.Biochemical pharmacology · 2017
    Review
  17. Postviral Complications: Bacterial Pneumonia.Clinics in chest medicine · 2017
    Review
  18. Review
  19. Viral-bacterial co-infections in the respiratory tract.Current opinion in microbiology · 2017
    Review
  20. Influenza A and B co-infection: a case-control study and review of the literature.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jane C DengDivision of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
University of California, Los Angeles · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Mechanisms of Impaired Neutrophil Responses in PostInfluenza Bacterial PneumoniaR01HL108949 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DENG, JANE C · 2012 to 2016
$1.8M
NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1TR000124NHLBI NIH HHS NIH R01HL108949NHLBI NIH HHS R01 HL108949
6 · The paper itself

Abstract

Viral and bacterial respiratory tract infections are a leading cause of morbidity and mortality worldwide, despite the development of vaccines and potent antibiotics. Frequently, viruses and bacteria can co-infect the same host, resulting in heightened pathology and severity of illness compared to single infections. Bacterial superinfections have been a significant cause of death during every influenza pandemic, including the 2009 H1N1 pandemic. This review will analyze the epidemiology and global impact of viral and bacterial co-infections of the respiratory tract, with an emphasis on bacterial infections following influenza. We will next examine the mechanisms by which viral infections enhance the acquisition and severity of bacterial infections. Finally, we will discuss current management strategies for diagnosing and treating patients with suspected or confirmed viral-bacterial infections of the respiratory tract. Further investigation into the interactions between viral and bacterial infections is necessary for developing new therapeutic approaches aimed at mitigating the severity of co-infections.

Indexed as

AnimalsBacterial InfectionsBacterial Physiological PhenomenaCoinfectionHumansInfluenza A Virus, H1N1 SubtypeInfluenza, Humanbacterial pneumoniainfluenzapolymicrobial infectionsrespiratory viral infection

Identifiers

PMID24215379
PMCPMC3831167
OpenAlexW2035660866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.