Evidence map›Paper›PMID 24214916›Full record

ArticleAngewandte Chemie (International ed. in English)2013

Two-photon-triggered drug delivery in cancer cells using nanoimpellers.

Jonas Croissant, Marie Maynadier, Audrey Gallud, Harmel Peindy N'dongo, Jeff L Nyalosaso, Gaëlle Derrien, Clarence Charnay, Jean-Olivier Durand, Laurence Raehm, Françoise Serein-Spirau and 11 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Detour to success: photoswitchingChemical science · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Light: A Magical Tool for Controlled Drug Delivery.Advanced functional materials · 2020
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Chemiluminescence-initiated andChemical science · 2019
    Article
  14. Article
  15. Article
  16. Molecular rotary motors: Unidirectional motion around double bonds.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jonas CroissantInstitut Charles Gerhardt Montpellier, UMR-5253 CNRS-UM2-ENSCM-UM1, cc 1701, Place Eugène Bataillon, 34095 Montpellier Cedex 05 (France).
Marie Maynadier
Audrey Gallud
Harmel Peindy N'dongo
Jeff L Nyalosaso
Gaëlle Derrien
Clarence Charnay
Jean-Olivier Durand
Laurence Raehm
Françoise Serein-Spirau
Nathalie Cheminet
Thibaut Jarrosson
Olivier Mongin
Mireille Blanchard-Desce
Magali Gary-Bobo
Marcel Garcia
Jie Lu
Fuyuhiko Tamanoi
Derrick Tarn
Tania M Guardado-Alvarez
Jeffrey I Zink

Funding

Nanovalve Platform: Targeted, Controlled, Release of Anticancer DrugsR01CA133697 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NEL, ANDRE ELIAS, STODDART, JAMES FRASER · 2010 to 2014
$2.1M
NCI NIH HHS CA133697NCI NIH HHS R01 CA133697
6 · The paper itself

Abstract

A therapy of cancer cells: Two-photon-triggered camptothecin delivery with nanoimpellers was studied in MCF-7 breast cancer cells. A fluorophore with a high two-photon absorption cross-section was first incorporated in the nanoimpellers. Fluorescence resonance energy transfer (FRET) from the fluorophore to the azobenzene moiety was demonstrated.

Indexed as

Azo CompoundsDrug Delivery SystemsHumansNanoparticlesNeoplasmsazobenzeneAzo Compoundsazobenzenecancerdrug deliverymesoporous materialstwo-photon excitation

Identifiers

PMID24214916
PMCPMC3940420

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.