Evidence map›Paper›PMID 24214409›Full record

ArticleMicrobiologyOpen2013

Developing an international Pseudomonas aeruginosa reference panel.

Anthony De Soyza, Amanda J Hall, Eshwar Mahenthiralingam, Pavel Drevinek, Wieslaw Kaca, Zuzanna Drulis-Kawa, Stoyanka R Stoitsova, Veronika Toth, Tom Coenye, James E A Zlosnik and 13 more

Abstract read
In one paragraph

Article in MicrobiologyOpen, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed.

  1. Article
  2. Article
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  5. Interference ofPharmaceuticals (Basel, Switzerland) · 2025
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  8. Complementary killing activities ofAntimicrobial agents and chemotherapy · 2025
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  12. Diversification ofMicroorganisms · 2025
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  13. AvirulentmicroLife · 2025
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  14. Article
  15. Article
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  17. Article
  18. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Anthony De SoyzaInstitute of Cellular Medicine, Newcastle University, Newcastle, U.K.
Amanda J Hall
Eshwar Mahenthiralingam
Pavel Drevinek
Wieslaw Kaca
Zuzanna Drulis-Kawa
Stoyanka R Stoitsova
Veronika Toth
Tom Coenye
James E A Zlosnik
Jane L Burns
Isabel Sá-Correia
Daniel De Vos
Jean-Paul Pirnay
Timothy J Kidd
David Reid
Jim Manos
Jens Klockgether
Lutz Wiehlmann
Burkhard Tümmler
Siobhán McClean
Craig Winstanley
EU FP7 funded COST Action BM1003 “Cell surface virulence determinants of cystic fibrosis pathogens”

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
NIDDK NIH HHS P30 DK089507NIDDK NIH HHS P30 DK 89507
6 · The paper itself

Abstract

Pseudomonas aeruginosa is a major opportunistic pathogen in cystic fibrosis (CF) patients and causes a wide range of infections among other susceptible populations. Its inherent resistance to many antimicrobials also makes it difficult to treat infections with this pathogen. Recent evidence has highlighted the diversity of this species, yet despite this, the majority of studies on virulence and pathogenesis focus on a small number of strains. There is a pressing need for a P. aeruginosa reference panel to harmonize and coordinate the collective efforts of the P. aeruginosa research community. We have collated a panel of 43 P. aeruginosa strains that reflects the organism's diversity. In addition to the commonly studied clones, this panel includes transmissible strains, sequential CF isolates, strains with specific virulence characteristics, and strains that represent serotype, genotype or geographic diversity. This focussed panel of P. aeruginosa isolates will help accelerate and consolidate the discovery of virulence determinants, improve our understanding of the pathogenesis of infections caused by this pathogen, and provide the community with a valuable resource for the testing of novel therapeutic agents.

Indexed as

Reference StandardsBiomedical ResearchCystic FibrosisHumansInternational CooperationMicrobiologyPneumonia, BacterialPseudomonas aeruginosaPseudomonas InfectionsCystic fibrosisgenotypepathogenPseudomonas aeruginosa

Identifiers

PMID24214409
PMCPMC3892346

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.