ReviewJournal of thrombosis and thrombolysis2014
Modeling thrombin generation: plasma composition based approach.
Review in Journal of thrombosis and thrombolysis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Systems Biology Approach for Personalized Hemostasis Correction.Journal of personalized medicine · 2022Article
- Semi-automated thrombin dynamics applying the ST Genesia thrombin generation assay.Frontiers in cardiovascular medicine · 2022Article
- Computationally Driven Discovery in Coagulation.Arteriosclerosis, thrombosis, and vascular biology · 2021Review
- Multiscale systems biology of trauma-induced coagulopathy.Wiley interdisciplinary reviews. Systems biology and medicine · 2018Review
- A Comparison of Healthy Infants and Adults with Respect to Indirect Microparticle Activity and the Parameters of the Thrombin Generation Test.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2016Article
- Systems Analysis of Thrombus Formation.Circulation research · 2016Review
- Circulating Microparticles Alter Formation, Structure, and Properties of Fibrin Clots.Scientific reports · 2015Article
- Mechanistic Modeling of the Effects of Acidosis on Thrombin Generation.Anesthesia and analgesia · 2015Article
- Real-time measurement of thrombin generation using continuous droplet microfluidics.Biomicrofluidics · 2014Article
- Global assays of hemostasis.Current opinion in hematology · 2014Review
- Novel mediators and biomarkers of thrombosis.Journal of thrombosis and thrombolysis · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Thrombin has multiple functions in blood coagulation and its regulation is central to maintaining the balance between hemorrhage and thrombosis. Empirical and computational methods that capture thrombin generation can provide advancements to current clinical screening of the hemostatic balance at the level of the individual. In any individual, procoagulant and anticoagulant factor levels together act to generate a unique coagulation phenotype (net balance) that is reflective of the sum of its developmental, environmental, genetic, nutritional and pharmacological influences. Defining such thrombin phenotypes may provide a means to track disease progression pre-crisis. In this review we briefly describe thrombin function, methods for assessing thrombin dynamics as a phenotypic marker, computationally derived thrombin phenotypes versus determined clinical phenotypes, the boundaries of normal range thrombin generation using plasma composition based approaches and the feasibility of these approaches for predicting risk.
Indexed as
Identifiers
24214371What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.