Evidence map›Paper›PMID 24213539›Full record

ArticleJournal of biomedical optics2013

Shear modulus imaging by direct visualization of propagating shear waves with phase-sensitive optical coherence tomography.

Shaozhen Song, Zhihong Huang, Thu-Mai Nguyen, Emily Y Wong, Bastien Arnal, Matthew O'Donnell, Ruikang K Wang

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Article
  2. Article
  3. Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Computational and structural biotechnology journal · 2023
    Review
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shaozhen SongUniversity of Washington, Department of Bioengineering, 3720 15th Avenue NE, Seattle, Washington 98195bUniversity of Dundee, School of Engineering, Physics and Mathematics, Dundee DD1 4HN, Scotland, UK.
Zhihong Huang
Thu-Mai Nguyen
Emily Y Wong
Bastien Arnal
Matthew O'Donnell
Ruikang K Wang

Funding

OPTICAL MICROANGIOGRAHY OF CEREBROVASCULAR PERFUSIONR01HL093140 · NHLBI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2008 to 2017
$4.2M
Volumetric imaging of blood perfusion and tissue morphology in the cochleaR01DC010201 · NIDCD · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2013
$2.2M
Sensitive tumor detection with magnetomotive imagingR01CA170734 · NCI · UNIVERSITY OF WASHINGTON · PI GAO, XIAOHU · 2012 to 2015
$1.8M
Non-invasive trapping and imaging of circulating tumor cells in the peripheral vaR01EB016034 · NIBIB · UNIVERSITY OF WASHINGTON · PI O'DONNELL, MATTHEW · 2013 to 2016
$1.7M
Label-free optical imaging of 3D structural and functional microcirculationsR01EB009682 · NIBIB · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2012
$1.7M
NCI NIH HHS R01 CA170734NCI NIH HHS R01CA170734NHLBI NIH HHS R01 HL093140NHLBI NIH HHS R01HL093140NIBIB NIH HHS R01 EB009682NIBIB NIH HHS R01EB009682NIBIB NIH HHS R01 EB016034NIBIB NIH HHS R01EB016034NIDCD NIH HHS R01 DC010201NIDCD NIH HHS R01DC010201
6 · The paper itself

Abstract

We propose an integrated method combining low-frequency mechanics with optical imaging to map the shear modulus within the biological tissue. Induced shear wave propagating in tissue is tracked in space and time using phase-sensitive optical coherence tomography (PhS-OCT). Local estimates of the shear-wave speed obtained from tracking results can image the local shear modulus. A PhS-OCT system remotely records depth-resolved, dynamic mechanical waves at an equivalent frame rate of ∼47  kHz with the high spatial resolution. The proposed method was validated by examining tissue-mimicking phantoms made of agar and light scattering material. Results demonstrate that the shear wave imaging can accurately map the elastic moduli of these phantoms.

Indexed as

AgarBiomechanical PhenomenaElasticity Imaging TechniquesElastic ModulusHumansImage Processing, Computer-AssistedModels, BiologicalPhantoms, ImagingReproducibility of ResultsTomography, Optical CoherenceAgar

Identifiers

PMID24213539
PMCPMC4019419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.