Evidence map›Paper›PMID 24213123›Full record

ArticleCancers2011

Nanoparticle delivery of natural products in the prevention and treatment of cancers: current status and future prospects.

Dhruba J Bharali, Imtiaz A Siddiqui, Vaqar M Adhami, Jean Christopher Chamcheu, Abdullah M Aldahmash, Hasan Mukhtar, Shaker A Mousa

Abstract read
In one paragraph

Article in Cancers, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  9. Flavokawain A alleviates the progression of mouse osteoarthritis: AnFrontiers in bioengineering and biotechnology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dhruba J BharaliThe Pharmaceutical Research Institute at Albany College of Pharmacy and Health Sciences, 1 Discovery Drive, Rensselaer, NY 12144, USA. shaker.mousa@acphs.edu.
Imtiaz A Siddiqui
Vaqar M Adhami
Jean Christopher Chamcheu
Abdullah M Aldahmash
Hasan Mukhtar
Shaker A Mousa

Funding

Investigative Dermatology Training Program at University of Wisconsin-MadisonT32AR055893 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI MUKHTAR, HASAN · 2009 to 2013
$984k
NIAMS NIH HHS T32 AR055893
6 · The paper itself

Abstract

The advent of nanotechnology has had a revolutionary impact on many aspects of 21st century life. Nanotechnology has provided an opportunity to explore new avenues that conventional technologies have been unable to make an impact on for diagnosis, prevention, and therapy of different diseases, and of cancer in particular. Entities in nanometer sizes are excellent platforms to incorporate various drugs or active materials that can be delivered effectively to the desired action site without compromising the activity of the incorporated drug or material. In particular, nanotechnology entities can be used to deliver conventional natural products that have poor solubility or a short half life. Conventional natural products used with entities in nanometer sizes enable us to solve many of the inherent problems (stability, solubility, toxicity) associated with natural products, and also provide a platform for targeted delivery to tumor sites. We recently introduced the novel concept of using nanotechnology for enhancing the outcome of chemoprevention, which we called 'nanochemoprevention'. This idea was subsequently exploited by several laboratories worldwide and has now become an advancing field in chemoprevention research. This review examines some of the applications of nanotechnology for cancer prevention and therapy using natural products.

Identifiers

PMID24213123
PMCPMC3763408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.