ArticleCancers2011
Gold nanostructures as a platform for combinational therapy in future cancer therapeutics.
Article in Cancers, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Redox-modulating metallic nanoparticles: mechanistic insights into pharmacological activity and cellular therapeutics.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Comparative DFT investigation of glutathione-mediated drug release fromJournal of molecular modeling · 2026Article
- Impacts of loading thymoquinone to gold or silver nanoparticles on the efficacy of anti-tumor treatments in breast cancer with or without chemotherapeutic cisplatin.BMC biotechnology · 2025Article
- Nanoparticles in Cancer Diagnosis and Treatment.Materials (Basel, Switzerland) · 2023Review
- Gold Nanorods as Radiopharmaceutical Carriers: Preparation and Preliminary Radiobiological In Vitro Tests.Nanomaterials (Basel, Switzerland) · 2023Article
- Review
- Preparation, toxicity reduction and radiation therapy application of gold nanorods.Journal of nanobiotechnology · 2021Review
- Investigation of Nano-Bio Interactions within a Pancreatic Tumor Microenvironment for the Advancement of Nanomedicine in Cancer Treatment.Current oncology (Toronto, Ont.) · 2021Article
- Nanoparticles: A New Approach to Upgrade Cancer Diagnosis and Treatment.Nanoscale research letters · 2021Review
- Modulation of the Microtubule Network for Optimization of Nanoparticle Dynamics for the Advancement of Cancer Nanomedicine.Bioengineering (Basel, Switzerland) · 2020Article
- Noninvasive imaging of tumor hypoxia after nanoparticle-mediated tumor vascular disruption.PloS one · 2020Article
- Modulation of gold nanoparticle mediated radiation dose enhancement through synchronization of breast tumor cell population.The British journal of radiology · 2019Article
- In Vitro Cytotoxicity of Folate-Silica-Gold Nanorods on Mouse Acute Lymphoblastic Leukemia and Spermatogonial Cells.Cell journal · 2019Article
- Gold Nanoparticles as a Photothermal Agent in Cancer Therapy: The Thermal Ablation Characteristic Length.Molecules (Basel, Switzerland) · 2018Article
- Gold Nanoparticles-enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa Cells.Scientific reports · 2018Article
- Effect of gold nanoparticles on radiation doses in tumor treatment: a Monte Carlo study.Lasers in medical science · 2017Article
- Article
- Plasmon-Enhanced Photocurrent using Gold Nanoparticles on a Three-Dimensional TiOScientific reports · 2017Article
- Advanced Functional Nanomaterials for Theranostics.Advanced functional materials · 2017Article
- Fabrication of Metal Nanoparticles from Fungi and Metal Salts: Scope and Application.Nanoscale research letters · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The field of nanotechnology is currently undergoing explosive development on many fronts. The technology is expected to generate innovations and play a critical role in cancer therapeutics. Among other nanoparticle (NP) systems, there has been tremendous progress made in the use of spherical gold NPs (GNPs), gold nanorods (GNRs), gold nanoshells (GNSs) and gold nanocages (GNCs) in cancer therapeutics. In treating cancer, radiation therapy and chemotherapy remain the most widely used treatment options and recent developments in cancer research show that the incorporation of gold nanostructures into these protocols has enhanced tumor cell killing. These nanostructures further provide strategies for better loading, targeting, and controlling the release of drugs to minimize the side effects of highly toxic anticancer drugs used in chemotherapy and photodynamic therapy. In addition, the heat generation capability of gold nanostructures upon exposure to UV or near infrared light is being used to damage tumor cells locally in photothermal therapy. Hence, gold nanostructures provide a versatile platform to integrate many therapeutic options leading to effective combinational therapy in the fight against cancer. In this review article, the recent progress in the development of gold-based NPs towards improved therapeutics will be discussed. A multifunctional platform based on gold nanostructures with targeting ligands, therapeutic molecules, and imaging contrast agents, holds an array of promising directions for cancer research.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.