ArticleCancers2010
Pain management in pancreatic cancer.
Article in Cancers, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 49 citations in OpenAlex.
- Pain Relieving Effect of Intraoperative Chemical Splanchnicectomy of Celiac Ganglions in Patients with Resectable Pancreatic or Gastric Masses: A Randomized Clinical Trial.Pain research & management · 2020Trial
- Health-related quality of life in patients with a germline BRCA mutation and metastatic pancreatic cancer receiving maintenance olaparib.Annals of oncology : official journal of the European Society for Medical Oncology · 2019Trial
- Celiac plexus radiosurgery for retroperitoneal pain in advanced cancer: a pre-specified secondary analysis of health-related quality of life in a phase II single-arm trial.EClinicalMedicine · 2026Article
- Review
- Minimally invasive techniques versus opioids in patients with unresectable pancreatic cancer: a systematic review and meta-analysis of randomised controlled trials.Translational gastroenterology and hepatology · 2025Article
- Are measures and related symptoms of cachexia recorded as outcomes in gastrointestinal cancer chemotherapy clinical trials?Journal of cachexia, sarcopenia and muscle · 2024Article
- Palliative and supportive care underutilization for patients with locally advanced pancreatic cancer: review of the NCDB.ESMO gastrointestinal oncology · 2024Article
- Neuropancreatology: The Nervous System and Pain Management in Pancreatic Diseases.Life (Basel, Switzerland) · 2024Review
- 5HT2A modulation attenuates pancreatic cancer induced pain mouse model by inhibiting HDAC.Acta cirurgica brasileira · 2024Article
- Pre-Diagnosis Pain in Patients With Pancreatic Cancer Signals the Need for Aggressive Symptom Management.The oncologist · 2023Article
- Principles of Palliative and Supportive Care in Pancreatic Cancer: A Review.Biomedicines · 2023Review
- Treatment Costs and Social Burden of Pancreatic Cancer.Cancers · 2023Review
- Quality of Life in Patients with Pancreatic Cancer-A Literature Review.International journal of environmental research and public health · 2023Review
- Tissue clearing and 3D reconstruction of digitized, serially sectioned slides provide novel insights into pancreatic cancer.Med (New York, N.Y.) · 2023Review
- Palliative Therapies in Metastatic Pancreatic Cancer: Does Medicaid Expansion Make a Difference?Annals of surgical oncology · 2023Article
- Quercetin Attenuates Nitroglycerin-Induced Migraine Headaches by Inhibiting Oxidative Stress and Inflammatory Mediators.Nutrients · 2022Article
- Review
- Factors associated with successful response to neurolytic celiac plexus block in patients with upper abdominal cancer-related pain: a retrospective study.The Korean journal of pain · 2021Article
- Pancreas Cancer-Associated Pain Management.The oncologist · 2021Review
- Noninvasive celiac plexus radiosurgery in palliative treatment for patients with symptomatic pancreatic cancer.Contemporary oncology (Poznan, Poland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A majority of pancreatic cancer patients present with pain at the time of diagnosis. Pain management can be challenging in light of the aggressive nature of this cancer. Apart from conventional pharmacotherapy, timely treatment with neurolytic celiac plexus block (NCPB) has been shown to be of benefit. NCPB has demonstrated efficacious pain control in high quality studies with analgesic effects lasting one to two months. NCPB has also shown to decrease the requirements of narcotics, and thus decrease opioid related side effects. Another option for the control of moderate to severe pain is intrathecal therapy (IT). Delivery of analgesic medications intrathecally allows for lower dosages of medications and thus reduced toxicity. Both of the above mentioned interventional procedures have been shown to have low complication rates, and be safe and effective. Ultimately, comprehensive pancreatic cancer pain management necessitates understanding of pain mechanisms and delivery of sequential validated therapeutic interventions within a multidisciplinary patient care model.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.