ReviewPediatrics and neonatology2014
Asthma exacerbation in children: a practical review.
Review in Pediatrics and neonatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- MicroRNAs as Diagnostic and Therapeutic Biomarkers in Childhood Asthma: A Systematic Review with Bioinformatics Analysis.Journal of personalized medicine · 2026Review
- Prediction of daily childhood asthma exacerbation from ambient meteorological, environmental risk factors and respiratory viruses, Philadelphia, PA, 2011 to 2016.Environmental science and pollution research international · 2025Article
- Association of Allergy Specialty Care and Asthma Outcomes for Medicaid-Enrolled Children.The Journal of pediatrics · 2025Article
- Distinguishing Childhood Asthma Exacerbations from Stable Asthma: The Utility of Inflammatory White Blood Cell Biomarkers.Diagnostics (Basel, Switzerland) · 2024Article
- Linkage of serum ITIH4 with Th2 signature cytokine, inflammation, exacerbation risk and severity in childhood asthma.Biomarkers in medicine · 2024Article
- Knowledge, Attitudes, and Practices of Influenza Vaccination among Parents of Children with Asthma: A Cross-Sectional Study.Vaccines · 2023Article
- Elevated Neutrophil-to-Lymphocyte Ratio Is Associated with Severe Asthma Exacerbation in Children.Journal of clinical medicine · 2023Article
- Indoor Aeroallergen Sensitization and Associated Factors in Hospitalized Children with Asthma Exacerbations.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2023Article
- Probiotics in Children with Asthma.Children (Basel, Switzerland) · 2022Review
- MALT1 in asthma children: A potential biomarker for monitoring exacerbation risk and Th1/Th2 imbalance-mediated inflammation.Journal of clinical laboratory analysis · 2022Article
- The effect of the COVID-19 pandemic on non-COVID respiratory ED visits in Israel.The American journal of emergency medicine · 2022Article
- Vitamin D supplementation in childhood asthma: a systematic review and meta-analysis of randomised controlled trials.ERJ open research · 2022Article
- To determine the association between asthma severity and hospital admission measured by Pediatric Respiratory Assessment Measure (PRAM) score at Indus Hospital and Health Network, Karachi, Pakistan, 2020-2021.Pakistan journal of medical sciences · 2022Article
- Memory-like innate lymphoid cells in the pathogenesis of asthma.Frontiers in immunology · 2022Review
- Could Interleukin-33 (IL-33) Govern the Outcome of an Equine Influenza Virus Infection? Learning from Other Species.Viruses · 2021Review
- The effect of the COVID-19 lockdown on children with asthma-related symptoms: A tertiary care center experience.Pediatric pulmonology · 2021Article
- Reduced JKAP correlates with advanced disease features, inflammation, as well as increased exacerbation risk and severity in asthmatic children.Irish journal of medical science · 2021Article
- Asthma attacks in children are always preceded by poor asthma control: myth or maxim?Breathe (Sheffield, England) · 2020Article
- The economic burden of medical treatment of children with asthma in China.BMC pediatrics · 2020Article
- Global Mapping of Research Trends on Interventions to Improve Health-Related Quality of Life in Asthma Patients.International journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is the most common chronic lower respiratory tract disease in childhood throughout the world. Despite advances in asthma management, acute exacerbations continue to be a major problem in patients and they result in a considerable burden on direct/indirect health care providers. A severe exacerbation occurring within 1 year is an independent risk factor. Respiratory tract viruses have emerged as the most frequent triggers of exacerbations in children. It is becoming increasingly clear that interactions may exist between viruses and other triggers, increasing the likelihood of an exacerbation. In this study, we provide an overview of current knowledge about asthma exacerbations, including its definition, impact on health care providers, and associated factors. Prevention management in intermittent asthma as well as intermittent wheeze in pre-school children and those with persistent asthma are discussed. Our review findings support the importance of controlling persistent asthma, as indicated in current guidelines. In addition, we found that early episodic intervention appeared to be crucial in preventing severe attacks and future exacerbations. Besides the use of medication, timely education after an exacerbation along with a comprehensive plan in follow up is also vitally important.
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