Evidence map›Paper›PMID 24210174›Full record

ArticleMolecular cell2013

Linking the Enzymes that Unlink DNA.

Steven J Brill

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Making the bend: DNA tertiary structure and protein-DNA interactions.International journal of molecular sciences · 2014
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Steven J BrillDepartment of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA. Electronic address: brill@cabm.rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

Genomic Stability and RecQ DNA Helicases in YeastR01GM071268 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI BRILL, STEVEN J. · 2004 to 2012
$2.5M
Mechanism of the BLM/Sgs1 Helicase ComplexR01GM101613 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI BRILL, STEVEN J. · 2012 to 2015
$1.3M
NIGMS NIH HHS R01 GM071268NIGMS NIH HHS R01 GM101613
6 · The paper itself

Abstract

Two papers in this issue, Castor et al. (2013) and Wyatt et al. (2013), and a third in Cell Reports, Garner et al. (2013), demonstrate that the scaffold protein SLX4 coordinates multiple nucleases in order to effectively resolve Holliday junctions and repair interstrand crosslinks (ICLs) in mammalian cells.

Indexed as

DNA, CruciformDNA RepairAnimalsDNA-Binding ProteinsEndodeoxyribonucleasesEndonucleasesHumansDNA-Binding ProteinsDNA, CruciformEme1 protein, mouseEndodeoxyribonucleasesEndonucleasesMus81 protein, mouseSLX1 protein, mouse

Identifiers

PMID24210174
PMCPMC4126409
OpenAlexW2093899720

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.