ArticleComparative medicine2013
Surgical methods for full-thickness skin grafts to induce alopecia areata in C3H/HeJ mice.
Article in Comparative medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Functional interrogation of lymphocyte subsets in alopecia areata using single-cell RNA sequencing.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Selective Janus kinase 1 inhibition resolves inflammation and restores hair growth offering a viable treatment option for alopecia areata.Skin health and disease · 2023Article
- Developmental plasticity allows outside-in immune responses by resident memory T cells.Nature immunology · 2020Article
- Migration and Function of Memory CD8The Journal of investigative dermatology · 2020Review
- Induction of alopecia areata in C3H/HeJ mice using polyinosinic-polycytidylic acid (poly[I:C]) and interferon-gamma.Scientific reports · 2018Article
- Article
- Alopecia areata.Nature reviews. Disease primers · 2017Review
- Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies.Autoimmunity reviews · 2016Review
- Dermal lymphatic dilation in a mouse model of alopecia areata.Experimental and molecular pathology · 2016Article
- Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening.Methods in molecular biology (Clifton, N.J.) · 2016Article
- Animal Models for Alopecia Areata: What and Where?The journal of investigative dermatology. Symposium proceedings · 2015Review
- Crisp1 and alopecia areata in C3H/HeJ mice.Experimental and molecular pathology · 2014Article
- What causes alopecia areata?Experimental dermatology · 2013Review
- Alopecia Areata: Review of Epidemiology, Clinical Features, Pathogenesis, and New Treatment Options.International journal of trichologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Alopecia areata is a cell-mediated autoimmune disease of humans and many domestic and laboratory animal species. C3H/HeJ inbred mice spontaneously develop alopecia areata at a low frequency (approximately 20% by 12 mo of age). Transferring full-thickness skin grafts from affected, older mice to young mice of the same strain reliably reproduces alopecia areata, thus enabling investigators to study disease pathogenesis or intervention with a variety of therapeutic approaches. We here describe in detail how to perform full-thickness skin grafts and the follow-up procedures necessary to consistently generate mice with alopecia areata. These engrafted mice can be used to study the pathogenesis of cell-mediated autoimmune disease and for drug-efficacy trials. This standard protocol can be used for many other purposes when studying abnormal skin phenotypes in laboratory mice.
Indexed as
Identifiers
24210015PMC3796749W77626720What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.