ArticleBiophysical journal2013
Coherent neutron scattering and collective dynamics in the protein, GFP.
Article in Biophysical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Spatially confined protein assembly in hierarchical mesoporous metal-organic framework.Nature communications · 2023Article
- Experimental mapping of short-wavelength phonons in proteins.Innovation (Cambridge (Mass.)) · 2022Article
- Substrate Binding Stiffens Aspartate Aminotransferase by Altering the Enzyme Picosecond Vibrational Dynamics.ACS omega · 2020Article
- Determination of functional collective motions in a protein at atomic resolution using coherent neutron scattering.Science advances · 2016Article
- On scattered waves and lipid domains: detecting membrane rafts with X-rays and neutrons.Soft matter · 2015Article
- Rigidity, secondary structure, and the universality of the boson peak in proteins.Biophysical journal · 2014Article
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Authors and funding
6 authors.
Funding
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Abstract
Collective dynamics are considered to be one of the major properties of soft materials, including biological macromolecules. We present coherent neutron scattering studies of the low-frequency vibrations, the so-called boson peak, in fully deuterated green fluorescent protein (GFP). Our analysis revealed unexpectedly low coherence of the atomic motions in GFP. This result implies a low amount of in-phase collective motion of the secondary structural units contributing to the boson peak vibrations and fast conformational fluctuations on the picosecond timescale. These observations are in contrast to earlier studies of polymers and glass-forming systems, and suggest that random or out-of-phase motions of the β-strands contribute greater than two-thirds of the intensity to the low-frequency vibrational spectra of GFP.
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