Evidence map›Paper›PMID 24209497›Full record

ReviewLipids in health and disease2013

Nonalcoholic fatty liver disease: molecular pathways and therapeutic strategies.

Yue Ye Huang, Aaron M Gusdon, Shen Qu

Abstract readReview
In one paragraph

Review in Lipids in health and disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  17. Article
  18. Article
  19. Endocrine causes of nonalcoholic fatty liver disease.World journal of gastroenterology · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yue Ye Huang
Aaron M Gusdon
Shen QuDepartment of Endocrinology and Metabolism, Shanghai 10th People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China. qushencn@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Along with rising numbers of patients with metabolic syndrome, the prevalence of nonalcoholic fatty liver disease (NAFLD) has increased in proportion with the obesity epidemic. While there are no established treatments for NAFLD, current research is targeting new molecular mechanisms that underlie NAFLD and associated metabolic disorders. This review discusses some of these emerging molecular mechanisms and their therapeutic implications for the treatment of NAFLD. The basic research that has identified potential molecular targets for pharmacotherapy will be outlined.

Indexed as

CurcuminFatty Acid Synthase, Type IFatty LiverFibric AcidsForkhead Box Protein O1Forkhead Transcription FactorsGene Expression RegulationHumansLipid MetabolismLiverMitochondriaNon-alcoholic Fatty Liver DiseasePeroxisomesPPAR gammaPregnane X ReceptorProtective AgentsCurcuminFASN protein, humanFatty Acid Synthase, Type IFibric AcidsForkhead Box Protein O1Forkhead Transcription FactorsFOXO1 protein, humanPPAR gammaPregnane X ReceptorProtective AgentsReceptor, Farnesoid X-ActivatedReceptors, Cytoplasmic and NuclearReceptors, SteroidThiazolidinediones

Identifiers

PMID24209497
PMCPMC3827997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.