ReviewEmerging infectious diseases2013
Tropheryma whipplei endocarditis.
Review in Emerging infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed.
- Molecular frequency ofNew microbes and new infections · 2026Article
- Rare but Critical: SevereClinical case reports · 2026Article
- Pulmonary infection caused byTranslational pediatrics · 2026Article
- A Recurrent Blood Culture-Negative Endocarditis Revealing Whipple's Disease.JACC. Case reports · 2026Article
- Article
- A new case ofOxford medical case reports · 2025Article
- Whipple's Disease as a Differential Diagnosis of Blood Culture-Negative Endocarditis: A Case Report.Arquivos brasileiros de cardiologia · 2025Article
- From Culture-Negative to DNA-Positive: The Molecular Revolution in Infective Endocarditis Diagnosis.Pathogens (Basel, Switzerland) · 2025Review
- Severe mitral valve papillary muscle rupture of isolated Whipple's endocarditis: a case report and review of the literature.Frontiers in cardiovascular medicine · 2025Article
- Whipple's endocarditis diagnosed non-invasively with plasma microbial cell-free DNA sequencing.IDCases · 2025Article
- Pulmonary infection caused by Tropheryma whipplei: a case report and review of the literature.Journal of medical case reports · 2024Review
- [Endocarditis and ischemic stroke of rare cause].Innere Medizin (Heidelberg, Germany) · 2024Article
- Tropheryma whipplei Endocarditis Presenting as Valvulopathy and Multiple Septic Emboli.Journal of general internal medicine · 2024Article
- Culture-negative endocarditis with multifocal spread and flail mitral valve leaflet: a case report.Annals of medicine and surgery (2012) · 2024Article
- [Chronic Tropheryma whipplei infection: an important differential diagnosis of refractory polyarthritis].Zeitschrift fur Rheumatologie · 2023Article
- Updates in Culture-Negative Endocarditis.Pathogens (Basel, Switzerland) · 2023Review
- Prosthetic valve endocarditis secondary to Tropheryma whipplei in a patient with chronic polyarthritis.Journal of cardiothoracic surgery · 2023Article
- An unusual presentation of a rare disease: acute upper limb ischemia as the presenting symptom of Whipple's Endocarditis, a case report.BMC infectious diseases · 2023Article
- Treatment refractory arthritis and stroke - A case of infective endocarditis caused byIDCases · 2023Article
- A Massive Number of ExtracellularFrontiers in immunology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tropheryma whipplei endocarditis differs from classic Whipple disease, which primarily affects the gastrointestinal system. We diagnosed 28 cases of T. whipplei endocarditis in Marseille, France, and compared them with cases reported in the literature. Specimens were analyzed mostly by molecular and histologic techniques. Duke criteria were ineffective for diagnosis before heart valve analysis. The disease occurred in men 40-80 years of age, of whom 21 (75%) had arthralgia (75%); 9 (32%) had valvular disease and 11 (39%) had fever. Clinical manifestations were predominantly cardiologic. Treatment with doxycycline and hydroxychloroquine for at least 12 months was successful. The cases we diagnosed differed from those reported from Germany, in which arthralgias were less common and previous valve lesions more common. A strong geographic specificity for this disease is found mainly in eastern-central France, Switzerland, and Germany. T. whipplei endocarditis is an emerging clinical entity observed in middle-aged and older men with arthralgia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.