ArticleAIDS research and human retroviruses2014
Genome sequence of a novel HIV-1 circulating recombinant form (CRF64_BC) identified from Yunnan, China.
Article in AIDS research and human retroviruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Unraveling HIV-1 transmission patterns through molecular surveillance in a hotspot in Yunnan Province, China.Scientific reports · 2025Article
- HIV-1 genetic diversity a challenge for AIDS vaccine development: a retrospective bibliometric analysis.Human vaccines & immunotherapeutics · 2022Article
- Using molecular network analysis to explore the characteristics of HIV-1 transmission in a China-Myanmar border area.PloS one · 2022Article
- Identification of a New HIV-1 BC Intersubtype Circulating Recombinant Form (CRF108_BC) in Spain.Viruses · 2021Article
- The origin and spread of CRF85_BC, driven by heterosexual transmission among older people in Sichuan, China.BMC infectious diseases · 2020Article
- Spatial clusters of HIV-1 genotypes in a recently infected population in Yunnan, China.BMC infectious diseases · 2019Article
- The changing HIV-1 genetic characteristics and transmitted drug resistance among recently infected population in Yunnan, China.Epidemiology and infection · 2018Article
- Article
- HIV-1 molecular epidemiology among newly diagnosed HIV-1 individuals in Hebei, a low HIV prevalence province in China.PloS one · 2017Article
- Article
- The Genomic Signature of Population Reconnection Following Isolation: From Theory to HIV.G3 (Bethesda, Md.) · 2015Article
- HIV Epidemic in Asia: Implications for HIV Vaccine and Other Prevention Trials.AIDS research and human retroviruses · 2015Review
- Article
- Development of an HIV-1 Subtype Panel in China: Isolation and Characterization of 30 HIV-1 Primary Strains Circulating in China.PloS one · 2015Article
- Evolving molecular epidemiological profile of human immunodeficiency virus 1 in the southwest border of China.PloS one · 2014Article
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10 authors.
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Abstract
We report a novel HIV-1 circulating recombinant form (CRF64_BC) that was isolated from five epidemiologically unlinked HIV-infected persons in Yunnan province. CRF64_BC was composed of subtype B and subtype C, with five short subtype B segments inserted into the subtype C backbone. Phylogenetic analysis demonstrated that the C subregion was correlated with the India C lineage, which was transmitted into China in the early 1990s. The evolutionary history of the B subregion was not as clear as the C subregion, as the short length of this region yielded poor phylogenetic results. Dehong is considered the epicenter of HIV-1 in China, and recombinant strains such as CRF07_BC and CRF08_BC, which also originated from this region, have spread widely in China. The newly emerged CRF64_BC increases the complexity of the HIV epidemic in China and complicates the development of subtype-specific tools against HIV transmission.
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