Evidence map›Paper›PMID 24205865›Full record

ReviewFEMS yeast research2014

Aging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicans.

Su-Ju Lin, Nicanor Austriaco

Abstract readReview
In one paragraph

Review in FEMS yeast research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
  2. Characterization of P-type HMolecular genetics and genomics : MGG · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Potential Anti-International journal of molecular sciences · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Extension of chronological lifespan in Schizosaccharomyces pombe.Genes to cells : devoted to molecular & cellular mechanisms · 2021
    Review
  15. Review
  16. Article
  17. Article
  18. The Antiaging Effect of Active Fractions andAntioxidants (Basel, Switzerland) · 2020
    Article
  19. Microorganisms · 2020
    Review
  20. The Transcription Factor Stp2 Is Important forFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Su-Ju LinDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, CA, USA.
Nicanor Austriaco

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Bongsup P Cho · 2012 to 2026
$63.6M
Understanding the Regulation of NAD+Homeostasis and SignalingR01GM102297 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LIN, SU-JU · 2012 to 2019
$2.2M
Genetic Identification of Sulforaphane's Mechanism of Action in Yeast Cell DeathR15GM094712 · NIGMS · PROVIDENCE COLLEGE · PI AUSTRIACO, NICANOR · 2010 to 2010
$310k
NIGMS NIH HHS 8 P20 GM103430-12NIGMS NIH HHS P20 GM103430NIGMS NIH HHS R01 GM102297NIGMS NIH HHS R01-GM102297NIGMS NIH HHS R15 GM094712NIGMS NIH HHS R15-GM094712
6 · The paper itself

Abstract

How do cells age and die? For the past 20 years, the budding yeast, Saccharomyces cerevisiae, has been used as a model organism to uncover the genes that regulate lifespan and cell death. More recently, investigators have begun to interrogate the other yeasts, the fission yeast, Schizosaccharomyces pombe, and the human fungal pathogen, Candida albicans, to determine if similar longevity and cell death pathways exist in these organisms. After summarizing the longevity and cell death phenotypes in S. cerevisiae, this mini-review surveys the progress made in the study of both aging and programed cell death (PCD) in the yeast models, with a focus on the biology of S. pombe and C. albicans. Particular emphasis is placed on the similarities and differences between the two types of aging, replicative aging, and chronological aging, and between the three types of cell death, intrinsic apoptosis, autophagic cell death, and regulated necrosis, found in these yeasts. The development of the additional microbial models for aging and PCD in the other yeasts may help further elucidate the mechanisms of longevity and cell death regulation in eukaryotes.

Indexed as

Cell DeathCandida albicansModels, BiologicalSchizosaccharomycesTime FactorsagingapoptosisCandida albicanscell deathSaccharomyces cerevisiaeSchizosaccharomyces pombe

Identifiers

PMID24205865
PMCPMC4000287

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.