ReviewBioMed research international2013
Plasticity in the human visual cortex: an ophthalmology-based perspective.
Review in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 65 citations in OpenAlex.
- Initial Impairment and Recovery of Vision-Related Functioning in Participants With Acute Optic Neuritis From the RENEW Trial of Opicinumab.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2019Trial
- Comment on: Efficacy and safety of pilocarpine hydrochloride ophthalmic solution USP 1.25% w/v versus placebo ophthalmic solution for the treatment of presbyopia - A multicentric clinical trial.Indian journal of ophthalmology · 2026Article
- Cell and tissue reprogramming: Unlocking a new era in medical drug discovery.Pharmacological reviews · 2025Review
- Evolving Strategies in Amblyopia Management: From Traditional Therapies to Cutting-Edge Innovations.Cureus · 2025Review
- Video-evoked neuromarkers of visual function in age-related macular degeneration.Frontiers in human neuroscience · 2025Article
- Refractive prescribing for preschool children by optometrists in England.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023Article
- Placebo effect after visual restitution training: no eye-tracking controlled perimetric improvement after visual border stimulation in late subacute and chronic visual field defects after stroke.Frontiers in neurology · 2023Article
- Visuo-Acoustic Stimulation's Role in Synaptic Plasticity: A Review of the Literature.International journal of molecular sciences · 2021Review
- fMRI Retinotopic Mapping in Patients with Brain Tumors and Space-Occupying Brain Lesions in the Area of the Occipital Lobe.Cancers · 2021Article
- Efficacy of Perceptual Learning-Based Vision Training as an Adjuvant to Occlusion Therapy in the Management of Amblyopia: A Pilot Study.Vision (Basel, Switzerland) · 2021Article
- Eye-tracking-based visual field analysis (EFA): a reliable and precise perimetric methodology for the assessment of visual field defects.BMJ open ophthalmology · 2021Article
- Spectacle Independence After Cataract Surgery: A Prospective Study With a Multifocal Intraocular Lens.Medical hypothesis, discovery & innovation ophthalmology journal · 2020Article
- Cerebral Modifications and Visual Pathway Reorganization in Maculopathy: A Systematic Review.Frontiers in neuroscience · 2020Review
- Enhanced Visual Attentional Modulation in Patients with Inherited Peripheral Retinal Degeneration in the Absence of Cortical Degeneration.Neural plasticity · 2019Article
- Assessment of Opicinumab in Acute Optic Neuritis Using Multifocal Visual Evoked Potential.CNS drugs · 2018Article
- Rapid neuroadaptation to surgically-induced aniseikonia in a 17-year-old patient with high preoperative anisometropia: A case report.American journal of ophthalmology case reports · 2018Article
- Changes of Visual Pathway and Brain Connectivity in Glaucoma: A Systematic Review.Frontiers in neuroscience · 2018Article
- Brain activity in the right-frontal pole and lateral occipital cortex predicts successful post-operatory outcome after surgery for anterior glenoumeral instability.Scientific reports · 2017Article
- Primary visual cortical remapping in patients with inherited peripheral retinal degeneration.NeuroImage. Clinical · 2017Article
- Fractality of sensations and the brain health: the theory linking neurodegenerative disorder with distortion of spatial and temporal scale-invariance and fractal complexity of the visible world.Frontiers in aging neuroscience · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroplasticity refers to the ability of the brain to reorganize the function and structure of its connections in response to changes in the environment. Adult human visual cortex shows several manifestations of plasticity, such as perceptual learning and adaptation, working under the top-down influence of attention. Plasticity results from the interplay of several mechanisms, including the GABAergic system, epigenetic factors, mitochondrial activity, and structural remodeling of synaptic connectivity. There is also a downside of plasticity, that is, maladaptive plasticity, in which there are behavioral losses resulting from plasticity changes in the human brain. Understanding plasticity mechanisms could have major implications in the diagnosis and treatment of ocular diseases, such as retinal disorders, cataract and refractive surgery, amblyopia, and in the evaluation of surgical materials and techniques. Furthermore, eliciting plasticity could open new perspectives in the development of strategies that trigger plasticity for better medical and surgical outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.