Evidence map›Paper›PMID 24205446›Full record

ArticleJournal of carcinogenesis & mutagenesis2013

Influence of Stromal Components on Lung Cancer Carcinogenesis.

Laurie A Shuman Moss, William G Stetler-Stevenson

Abstract read
In one paragraph

Article in Journal of carcinogenesis & mutagenesis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Laurie A Shuman MossRadiation Oncology Branch, National Cancer Institute, NIH, Bethesda, MD 20892-1500, USA.
William G Stetler-Stevenson

Funding

Preclinical development of TIMP-2 as a biologic therapy for cancerZIABC011204 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI STETLER-STEVENSON, WILLIAM · 2009 to 2024
$14.5M
The Role of TIMPs in Cell Growth, Tumor Progression and MetastasisZIASC009179 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI STETLER-STEVENSON, WILLIAM · 2009 to 2024
$9.7M
Intramural NIH HHS ZIA SC009179
6 · The paper itself

Abstract

The association between tumor growth and angiogenesis was first observed over 100 years ago. Since then, research has shown the dependence of tumor growth on angiogenesis and the ability of cancer cells to alter the stromal microenvironment. Technological advancements have enabled researchers to identify cell types within a tumor, identify chemokines, cytokines, and growth factors secreted by tumor cells, show the interaction between tumor cells and stroma, and investigate the function of distinct genes using knockout and transgenic mouse technology. This review provides an overview of tumor growth, emphasizing research using

Indexed as

FibrinogenFibronectinLung cancerMatrix metalloproteinasesPlasminogenTIMPsVEGF

Identifiers

PMID24205446
PMCPMC3818080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.