SynthesisPloS one2013
The risk of metabolic syndrome in patients with rheumatoid arthritis: a meta-analysis of observational studies.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- The Effect of Dietary Interventions on Chronic Inflammatory Diseases in Relation to the Microbiome: A Systematic Review.Nutrients · 2021Pooled it
- Metabolic syndrome and its components among rheumatoid arthritis patients: A comprehensive updated systematic review and meta-analysis.PloS one · 2017Pooled it
- Subclinical Hypothyroidism and Type 2 Diabetes: A Systematic Review and Meta-Analysis.PloS one · 2015Pooled it
- Vasodilator function worsens after cessation of tumour necrosis factor inhibitor therapy in patients with rheumatoid arthritis only if a flare occurs.Clinical rheumatology · 2018Trial
- Prevalence and contributing factors of metabolic syndrome in rheumatoid arthritis patients.BMC endocrine disorders · 2024Article
- Prevalence of Steatotic Liver Disease Among US Adults with Rheumatoid Arthritis.Digestive diseases and sciences · 2024Article
- Rheumatoid arthritis, cardiometabolic comorbidities, and related conditions: need to take action.Frontiers in medicine · 2024Review
- Potential Benefits of Antioxidant Phytochemicals in Type 2 Diabetes.Molecules (Basel, Switzerland) · 2023Review
- TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease.Nature communications · 2022Article
- High prevalence of undiagnosed impaired glucose tolerance in patients with rheumatoid arthritis.SAGE open medicine · 2022Article
- Metabolic syndrome in rheumatoid arthritis patients: Relationship among its clinical components.Journal of clinical laboratory analysis · 2021Article
- Metabolic Syndrome and Atherogenic Indices in Rheumatoid Arthritis and their Relationship with Disease Activity: A Hospital-based Study from Northeast India.Journal of translational internal medicine · 2020Article
- Chronic inflammation in the etiology of disease across the life span.Nature medicine · 2019Review
- Sex and Cardiovascular Involvement in Inflammatory Joint Diseases.Clinical reviews in allergy & immunology · 2019Review
- Observational
- Cardiac Impairment in Rheumatoid Arthritis and Influence of Anti-TNFα Treatment.Clinical reviews in allergy & immunology · 2017Review
- The metabolic profile in early rheumatoid arthritis: a high prevalence of metabolic obesity.Rheumatology international · 2017Article
- Observational
- Managing cardiovascular risk in patients with inflammatory arthritis: practical considerations.Therapeutic advances in musculoskeletal disease · 2016Review
- Parasitic infection as a potential therapeutic tool against rheumatoid arthritis.Experimental and therapeutic medicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObservational studies suggest an association between the incidence of rheumatoid arthritis (RA) and the prevalence of metabolic syndrome (MetS). However, the relationship between RA and MetS is controversial and research in this area is currently lacking.
objectiveThe aim of this study was to assess whether the prevalence of MetS was higher in a group of RA patients compared to subjects without RA.
designA PubMed database search was conducted during April 2013 to identify observational studies of RA and risk of MetS. Reference lists of retrieved articles were also reviewed. Two authors independently extracted information on the study design, the characteristics of the study participants, exposure and outcome assessments, and the method used to control for potential confounding factors. A random-effects model was used for the risk estimates.
resultsOur meta-analysis of four cross-sectional controlled studies plus eight case-control studies involving a total of 2283 cases and 4403 controls identified a significant association between RA and risk of MetS, with an overall OR of 1.24 (95% CI, 1.03-1.50).
conclusionThis meta-analysis provides further evidence supporting patients with RA have a higher prevalence of MetS than subjects without RA. In addition, the geographic region of the population and the criteria used for MetS diagnosis could influence the association. However, these observations would need to be evaluated using prospective, randomized studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.