ArticlePloS one2013
Evaluation of non-invasive biological samples to monitor Staphylococcus aureus colonization in great apes and lemurs.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 41 citations in OpenAlex.
- Review of a decade of fauna research in Côte d'Ivoire with insights into wildlife health and zoonotic transmissions.One health (Amsterdam, Netherlands) · 2025Review
- Genomic and phenotypic characterization of staphylococci isolated from the skin of non-human primates.Microbiology (Reading, England) · 2025Article
- Epidemiology and zoonotic potential of Livestock-associated Staphylococcus aureus isolated at Tamil Nadu, India.BMC microbiology · 2023Article
- Zoonotic sources and the spread of antimicrobial resistance from the perspective of low and middle-income countries.Infectious diseases of poverty · 2023Review
- Viruses in sanctuary chimpanzees across Africa.American journal of primatology · 2023Article
- Viruses in saliva from sanctuary chimpanzees (Pan troglodytes) in Republic of Congo and Uganda.PloS one · 2023Article
- Investigation of methicillin-resistantVeterinary world · 2022Article
- Phylogenetic Groups, Pathotypes and Antimicrobial Resistance ofPathogens (Basel, Switzerland) · 2022Article
- Molecular Characterization of Methicillin-SensitivePathogens (Basel, Switzerland) · 2022Article
- A Review of Non-Invasive Sampling in Wildlife Disease and Health Research: What's New?Animals : an open access journal from MDPI · 2022Review
- Wild Animals Are Reservoirs and Sentinels ofAntibiotics (Basel, Switzerland) · 2021Review
- The Prevalence ofAnimals : an open access journal from MDPI · 2021Article
- Article
- A review of research in primate sanctuaries.Biology letters · 2020Review
- Review
- Prevalence of Methicillin-ResistantInternational journal of microbiology · 2020Article
- Carriage of Methicillin-resistantComparative medicine · 2019Article
- Association of Primate Veterinarians Guidelines For Mrsa Infections in Nonhuman Primates in Biomedical Research.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
- The human clone ST22 SCCmec IV methicillin-resistant Staphylococcus aureus isolated from swine herds and wild primates in Nepal: is man the common source?FEMS microbiology ecology · 2018Article
- The Pathogenesis of Staphylococcus aureus Eye Infections.Pathogens (Basel, Switzerland) · 2018Review
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionReintroduction of endangered animals as part of conservational programs bears the risk of importing human pathogens from the sanctuary to the natural habitat. One bacterial pathogen that serves as a model organism to analyze this transmission is Staphylococcus aureus as it can colonize and infect both humans and animals. The aim of this study was to evaluate the utility of various biological samples to monitor S. aureus colonization in great apes and lemurs.
methodsMucosal swabs from wild lemurs (n=25, Kirindy, Madagascar), feces, oral and genital swabs from captive chimpanzees (n=58, Ngamba and Entebbe, Uganda) and fruit wadges and feces from wild chimpanzees (n=21, Taï National Parc, Côte d'Ivoire) were screened for S. aureus. Antimicrobial resistance and selected virulence factors were tested for each isolate. Sequence based genotyping (spa typing, multilocus sequence typing) was applied to assess the population structure of S. aureus.
resultsOro-pharyngeal carriage of S. aureus was high in lemurs (72%, n=18) and captive chimpanzees (69.2%, n=27 and 100%, n=6, respectively). Wild chimpanzees shed S. aureus through feces (43.8, n=7) and fruit wadges (54.5, n=12). Analysis of multiple sampling revealed that two samples are sufficient to detect those animals which shed S. aureus through feces or fruit wadges. Genotyping showed that captive animals are more frequently colonized with human-associated S. aureus lineages.
conclusionOro-pharyngeal swabs are useful to screen for S. aureus colonization in apes and lemurs before reintroduction. Duplicates of stool and fruit wadges reliably detect S. aureus shedding in wild chimpanzees. We propose to apply these sampling strategies in future reintroduction programs to screen for S. aureus colonization. They may also be useful to monitor S. aureus in wild populations.
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