ArticlePloS one2013
Functional characterization of the poplar R2R3-MYB transcription factor PtoMYB216 involved in the regulation of lignin biosynthesis during wood formation.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 100 citations in OpenAlex.
- Structure, evolution, and roles of MYB transcription factors proteins in secondary metabolite biosynthetic pathways and abiotic stresses responses in plants: a comprehensive review.Frontiers in plant science · 2025Review
- Genome-wide identiffcation of the WRKY gene family in poplar and the positive role of PsnWRKY95 in response to cadmium stress.PloS one · 2025Article
- The Potential Role of Genic-SSRs in Driving Ecological Adaptation Diversity inInternational journal of molecular sciences · 2024Article
- Deciphering the intricate hierarchical gene regulatory network: unraveling multi-level regulation and modifications driving secondary cell wall formation.Horticulture research · 2024Article
- Lignin biosynthesis pathway repressors in gymnosperms: differential repressor domains as compared to angiosperms.Forestry research · 2024Review
- Histology, physiology, and transcriptomic and metabolomic profiling reveal the developmental dynamics of annual shoots in tree peonies (Horticulture research · 2023Article
- Association Mapping and Expression Analysis of the Genes Involved in the Wood Formation of Poplar.International journal of molecular sciences · 2023Article
- Wound-Induced Temporal Reprogramming of Gene Expression during Agarwood Formation inPlants (Basel, Switzerland) · 2023Article
- Peach DELLA Protein PpeDGYLA Is Not Degraded in the Presence of Active GA and Causes Dwarfism When Overexpressed in Poplar and Arabidopsis.International journal of molecular sciences · 2023Article
- Article
- Multiomics studies with co-transformation reveal microRNAs via miRNA-TF-mRNA network participating in wood formation inFrontiers in plant science · 2023Article
- MYB transcription factors-master regulators of phenylpropanoid biosynthesis and diverse developmental and stress responses.Plant cell reports · 2022Review
- The Regulation of Xylem Development by Transcription Factors and Their Upstream MicroRNAs.International journal of molecular sciences · 2022Review
- Dimerization of PtrMYB074 and PtrWRKY19 mediates transcriptional activation of PtrbHLH186 for secondary xylem development in Populus trichocarpa.The New phytologist · 2022Article
- Overexpression of PnMYB2 from Panax notoginseng induces cellulose and lignin biosynthesis during cell wall formation.Planta · 2022Article
- Molecular understanding of wood formation in trees.Forestry research · 2022Review
- Article
- MYB Transcription Factors and Its Regulation in Secondary Cell Wall Formation and Lignin Biosynthesis during Xylem Development.International journal of molecular sciences · 2021Review
- RNA Sequencing Reveals Phenylpropanoid Biosynthesis Genes and Transcription Factors forFrontiers in genetics · 2021Article
- Synergies and Entanglement in Secondary Cell Wall Development and Abiotic Stress Response in Trees.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Because of the importance of wood in many industrial applications, tremendous studies have been performed on wood formation, especially in lignin biosynthesis. MYB transcription factors (TFs), which consist of a large family of plant TFs, have been reported to directly regulate lignin biosynthetic genes in a number of plants. In this study, we describe the cloning and functional characterization of PtoMYB216, a cDNA isolated from Chinese white poplar (Populus tomentosa Carr.). PtoMYB216 encodes a protein belonging to the R2R3-MYB family and displays significant similarity with other MYB factors shown to regulate lignin synthesis in Arabidopsis. Gene expression profiling studies showed that PtoMYB216 mRNA is specifically expressed during secondary wall formation in wood. The 1.8-kb promoter sequence of PtoMYB216 was fused to the GUS coding sequence and introduced into wild-type A. thaliana. GUS expression was shown to be restricted to tissues undergoing secondary cell wall formation. Overexpression of PtoMYB216 specifically activated the expression of the upstream genes in the lignin biosynthetic pathway and resulted in ectopic deposition of lignin in cells that are normally unligninified. These results suggest that PtoMYB216 is specific transcriptional activators of lignin biosynthesis and involved in the regulation of wood formation in poplar.
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