Evidence map›Paper›PMID 24204613›Full record

SynthesisPloS one2013

Performance of shear wave elastography for differentiation of benign and malignant solid breast masses.

Guiling Li, De-Wei Li, Yu-Xiao Fang, Yi-Jiang Song, Zhu-Jun Deng, Jian Gao, Yan Xie, Tian-Sheng Yin, Li Ying, Kai-Fu Tang

Abstract readMeta-Analysis
In one paragraph

Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  14. Principles of ultrasound elastography.Abdominal radiology (New York) · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guiling LiInstitute of Genomic Medicine, Wenzhou Medical University, Wenzhou, P.R. China.
De-Wei Li
Yu-Xiao Fang
Yi-Jiang Song
Zhu-Jun Deng
Jian Gao
Yan Xie
Tian-Sheng Yin
Li Ying
Kai-Fu Tang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo perform a meta-analysis assessing the ability of shear wave elastography (SWE) to identify malignant breast masses.

methodsPubMed, the Cochrane Library, and the ISI Web of Knowledge were searched for studies evaluating the accuracy of SWE for identifying malignant breast masses. The diagnostic accuracy of SWE was evaluated according to sensitivity, specificity, and hierarchical summary receiver operating characteristic (HSROC) curves. An analysis was also performed according to the SWE mode used: supersonic shear imaging (SSI) and the acoustic radiation force impulse (ARFI) technique. The clinical utility of SWE for identifying malignant breast masses was evaluated using analysis of Fagan plot.

resultsA total of 9 studies, including 1888 women and 2000 breast masses, were analyzed. Summary sensitivities and specificities were 0.91 (95% confidence interval [CI], 0.88-0.94) and 0.82 (95% CI, 0.75-0.87) by SSI and 0.89 (95% CI, 0.81-0.94) and 0.91 (95% CI, 0.84-0.95) by ARFI, respectively. The HSROCs for SSI and ARFI were 0.92 (95% CI, 0.90-0.94) and 0.96 (95% CI, 0.93-0.97), respectively. SSI and ARFI were both very informative, with probabilities of 83% and 91%, respectively, for correctly differentiating between benign and malignant breast masses following a "positive" measurement (over the threshold value) and probabilities of disease as low as 10% and 11%, respectively, following a "negative" measurement (below the threshold value) when the pre-test probability was 50%.

conclusionsSWE could be used as a good identification tool for the classification of breast masses.

Indexed as

Elasticity Imaging TechniquesUltrasonography, MammaryAdultAgedBreastBreast NeoplasmsDiagnosis, DifferentialFemaleHumansMiddle AgedReproducibility of ResultsROC CurveSensitivity and Specificity

Identifiers

PMID24204613
PMCPMC3799848

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.