ArticlePloS one2013
Mechanical control of organ size in the development of the Drosophila wing disc.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- The TissueTractor: A Device for Applying Large Strains to Tissues and Cells for Simultaneous High-Resolution Live Cell Microscopy.Small methods · 2025Article
- Article
- The TissueTractor, a device for applying large strains to tissues and cells for simultaneous high-resolution live cell microscopy.bioRxiv : the preprint server for biology · 2024Article
- How Cell Geometry and Cellular Patterning Influence Tissue Stiffness.International journal of molecular sciences · 2022Article
- The wing imaginal disc.Genetics · 2022Article
- Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc.Nature communications · 2021Article
- The Geometry of Incompatibility in Growing Soft Tissues: Theory and Numerical Characterization.Journal of the mechanics and physics of solids · 2021Article
- Planar Differential Growth Rates Initiate Precise Fold Positions in Complex Epithelia.Developmental cell · 2019Article
- Hippo signalling during development.Development (Cambridge, England) · 2019Review
- Disentangling geometrical, viscoelastic and hyperelastic effects in force-displacement relationships of folded biological tissues.The European physical journal. E, Soft matter · 2019Article
- Statistics of noisy growth with mechanical feedback in elastic tissues.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Microfluidics on the fly: Inexpensive rapid fabrication of thermally laminated microfluidic devices for live imaging and multimodal perturbations of multicellular systems.Biomicrofluidics · 2019Article
- Force transduction by cadherin adhesions in morphogenesis.F1000Research · 2019Review
- Perspective: The promise of multi-cellular engineered living systems.APL bioengineering · 2018Article
- Mechanical characterization of disordered and anisotropic cellular monolayers.Physical review. E · 2018Article
- Article
- Challenging FRET-based E-Cadherin force measurements in Drosophila.Scientific reports · 2017Article
- Spatially Different Tissue-Scale Diffusivity Shapes ANGUSTIFOLIA3 Gradient in Growing Leaves.Biophysical journal · 2017Article
- Release of Applied Mechanical Loading Stimulates Intercellular Calcium Waves in Drosophila Wing Discs.Biophysical journal · 2017Article
- Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease.Seminars in cell & developmental biology · 2017Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Control of cessation of growth in developing organs has recently been proposed to be influenced by mechanical forces acting on the tissue due to its growth. In particular, it was proposed that stretching of the tissue leads to an increase in cell proliferation. Using the model system of the Drosophila wing imaginal disc, we directly stretch the tissue finding a significant increase in cell proliferation, thus confirming this hypothesis. In addition, we characterize the growth over the entire growth period of the wing disc finding a correlation between the apical cell area and cell proliferation rate. PACS NUMBERS: 87.19.lx, 87.18.Nq, 87.80.Ek, 87.17.Ee, 87.85.Xd.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.