ArticlePloS one2013
The effects of vector movement and distribution in a mathematical model of dengue transmission.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Modeling the effects of vector species composition and temperature on the risk of dengue virus.Bulletin of mathematical biology · 2026Article
- Increasing Effectiveness of Genetically Modifying Mosquito Populations: Risk Assessment of Releasing Blood-Fed Females.The American journal of tropical medicine and hygiene · 2021Article
- Disease-driven reduction in human mobility influences human-mosquito contacts and dengue transmission dynamics.PLoS computational biology · 2021Article
- Does Bangkok have a central role in the dengue dynamics of Thailand?Parasites & vectors · 2020Article
- Modeling the Heterogeneity of Dengue Transmission in a City.International journal of environmental research and public health · 2018Article
- Challenges in dengue research: A computational perspective.Evolutionary applications · 2018Review
- Seroprevalence of Dengue Antibodies in Three Urban Settings in Yucatan, Mexico.The American journal of tropical medicine and hygiene · 2018Article
- Article
- Genetic Evidence of Contemporary Dispersal of the Intermediate Snail Host of Schistosoma japonicum: Movement of an NTD Host Is Facilitated by Land Use and Landscape Connectivity.PLoS neglected tropical diseases · 2016Article
- DengueME: A Tool for the Modeling and Simulation of Dengue Spatiotemporal Dynamics.International journal of environmental research and public health · 2016Review
- Spatial distribution of an infectious disease in a small mammal community.Die Naturwissenschaften · 2015Article
- Towards a Hybrid Agent-based Model for Mosquito Borne Disease.Summer Computer Simulation Conference : (SCSC 2014) : 2014 Summer Simulation Multi-Conference : Monterey, California, USA, 6-10 July 2014. Summer Computer Simulation Conference (2014 : Monterey, Calif.) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundMathematical models have been used to study the dynamics of infectious disease outbreaks and predict the effectiveness of potential mass vaccination campaigns. However, models depend on simplifying assumptions to be tractable, and the consequences of making such assumptions need to be studied. Two assumptions usually incorporated by mathematical models of vector-borne disease transmission is homogeneous mixing among the hosts and vectors and homogeneous distribution of the vectors. METHODOLOGY/PRINCIPAL
findingsWe explored the effects of mosquito movement and distribution in an individual-based model of dengue transmission in which humans and mosquitoes are explicitly represented in a spatial environment. We found that the limited flight range of the vector in the model greatly reduced its ability to transmit dengue among humans. A model that does not assume a limited flight range could yield similar attack rates when transmissibility of dengue was reduced by 39%. A model in which mosquitoes are distributed uniformly across locations behaves similarly to one in which the number of mosquitoes per location is drawn from an exponential distribution with a slightly higher mean number of mosquitoes per location. When the models with different assumptions were calibrated to have similar human infection attack rates, mass vaccination had nearly identical effects. CONCLUSIONS/SIGNIFICANCE: Small changes in assumptions in a mathematical model of dengue transmission can greatly change its behavior, but estimates of the effectiveness of mass dengue vaccination are robust to some simplifying assumptions typically made in mathematical models of vector-borne disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.