ArticleFrontiers in plant science2013
A phenomics approach to the analysis of the influence of glutathione on leaf area and abiotic stress tolerance in Arabidopsis thaliana.
Article in Frontiers in plant science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Phenomics as an approach to Comparative Developmental Physiology.Frontiers in physiology · 2023Article
- Glutathione Metabolism in Plants under Stress: Beyond Reactive Oxygen Species Detoxification.Metabolites · 2021Review
- Metabolome Analysis Revealed the Mechanism of Exogenous Glutathione to Alleviate Cadmium Stress in Maize (Plants (Basel, Switzerland) · 2021Article
- Morphological Responses and Gene Expression of Grain Amaranth (Plants (Basel, Switzerland) · 2020Article
- Glutathione redox state plays a key role in flower development and pollen vigour.Journal of experimental botany · 2020Article
- All roads lead to growth: imaging-based and biochemical methods to measure plant growth.Journal of experimental botany · 2020Article
- Low-glutathione mutants are impaired in growth but do not show an increased sensitivity to moderate water deficit.PloS one · 2019Article
- Effects of Combined Low Glutathione with Mild Oxidative and Low Phosphorus Stress on the Metabolism ofFrontiers in plant science · 2017Article
- Comprehensive analysis of regulatory elements of the promoters of rice sulfate transporter gene family and functional characterization of OsSul1;1 promoter under different metal stress.Plant signaling & behavior · 2015Article
- The effects of redox controls mediated by glutathione peroxidases on root architecture in Arabidopsis thaliana.Journal of experimental botany · 2014Article
- Transporters in plant sulfur metabolism.Frontiers in plant science · 2014Review
- Thiol-based redox homeostasis and signaling.Frontiers in plant science · 2014Article
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Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reduced glutathione (GSH) is an abundant low molecular weight plant thiol. It fulfills multiple functions in plant biology, many of which remain poorly characterized. A phenomics approach was therefore used to investigate the effects of glutathione homeostasis on growth and stress tolerance in Arabidopsis thaliana. Rosette leaf area was compared in mutants that are either defective in GSH synthesis (cad2, pad2, and rax1) or the export of γ-glutamylcysteine and GSH from the chloroplast (clt) and in wild-type plants under standard growth conditions and following exposure to a range of abiotic stress treatments, including oxidative stress, water stress, and high salt. In the absence of stress, the GSH synthesis mutants had a significantly lower leaf area than the wild type. Conversely, the clt mutant has a greater leaf area and a significantly reduced lateral root density than the wild type. These findings demonstrate that cellular glutathione homeostasis exerts an influence on root architecture and on rosette area. An impaired capacity to synthesize GSH or a specific depletion of the cytosolic GSH pool did not adversely affect leaf area in plants exposed to short-term abiotic stress. However, the negative effects of long-term exposure to oxidative stress and high salt on leaf area were less marked in the GSH synthesis mutants than the wild type. These findings demonstrate the importance of cellular glutathione homeostasis in the regulation of plant growth under optimal and stress conditions.
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