Evidence map›Paper›PMID 24201685›Full record

ArticleObstetrics and gynecology2013

Characteristics associated with discontinuation of long-acting reversible contraception within the first 6 months of use.

Danielle S Grunloh, Teya Casner, Gina M Secura, Jeffrey F Peipert, Tessa Madden

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Obstetrics and gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 51 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 4 pooled it
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01986439 unknown statusnot on this map

The Contraceptive Choice Project

TypeobservationalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2007 to 2016Enrolled9,256ConditionsUnintended Pregnancy, Teen Births, Abortion, Contraception
NCT07658937 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians: ReSPECT Intervention Proof-of-Concept Testing

TypeinterventionalSponsorConnecticut Children's Medical CenterRan2026 to 2029Enrolled30ConditionsHealth-Related Quality-of-Life, Cancer, Health CommunicationArmsReSPECT
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 4 syntheses or guidelines pooled it, 128 citations in OpenAlex.

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  12. A 3-year Retrospective Review of Contraceptive Initiation, Continuation, Switching, and Pregnancy Among Adolescents and Young Adults.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
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  16. Reproductive Planning and the Choice of Long-acting Reversible Contraceptive Primary to Health: A Cross-Sectional Study.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
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  19. Reasons given by women for discontinuing the use of progestogen implants at Koster Hospital, North West province.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Danielle S GrunlohDivision of Clinical Research, Department of Obstetrics and Gynecology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Teya Casner
Gina M Secura
Jeffrey F Peipert
Tessa Madden
Washington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
EVALUATION AND TESTING OF A DECISION SUPPORT AID IN CONTRACEPTIVE DECISION MAKINGK23HD070979 · NICHD · WASHINGTON UNIVERSITY · PI MADDEN, TESSA · 2012 to 2014
$367k
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1TR000448NICHD NIH HHS K23 HD070979NICHD NIH HHS K23HD070979
6 · The paper itself

Abstract

objectiveTo measure discontinuation within 6 months among users of the levonorgestrel intrauterine system, copper intrauterine device (IUD), and etonogestrel implant and identify baseline characteristics associated with early discontinuation.

methodsThis was an analysis of the Contraceptive CHOICE Project, a cohort study of 9,256 participants provided with no-cost contraception and followed with telephone interviews at 3 and 6 months. We used logistic regression to investigate characteristics associated with early discontinuation of the two IUDs and implant and described reasons for discontinuation.

resultsA total of 6,167 participants were eligible for this analysis. Follow-up data were available for 5,928 participants; 5,495 (93%) were using their method at 6 months and 433 (7%) had discontinued. Discontinuation rates were 7.3%, 8.0%, and 6.9% for the levonorgestrel intrauterine system, copper IUD, and implant, respectively. After adjusting for age, race, marital status, low socioeconomic status, and history of sexually transmitted infection, we found that unmarried women were slightly more likely to discontinue compared with married women (adjusted odds ratio [OR] 1.26, 95% confidence interval [CI] 1.01-1.59 and adjusted OR 1.62, 95% CI 1.11-2.37, respectively). No other baseline characteristics, including younger age (14-19 years), were associated with early discontinuation. The most common reason given for discontinuation was cramping among IUD users and irregular or frequent bleeding among implant users.

conclusionRates of discontinuation of long-acting reversible contraception at 6 months is low and not increased in adolescents and young women. Intrauterine devices and the implant should be considered as first-line contraceptive options among all women to reduce unintended pregnancy. LEVEL OF EVIDENCE: : II.

Indexed as

Treatment RefusalAdolescentAdultBlack or African AmericanColicDrug ImplantsFemaleHumansIntrauterine Devices, CopperIntrauterine Devices, MedicatedMarital StatusMetrorrhagiaProspective StudiesSocial ClassTime FactorsWhite PeopleDrug Implants

Identifiers

PMID24201685
PMCPMC4051392
OpenAlexW1998923033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.