ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2014
Hounsfield units variations: impact on CT-density based conversion tables and their effects on dose distribution.
Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Can CT scan protocols used for radiotherapy treatment planning be adjusted to optimize image quality and patient dose? A systematic review.The British journal of radiology · 2017Pooled it
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- Dosimetric impact of material misassignment in linear Boltzmann transport equation-based external beam radiotherapy dose calculation.Radiological physics and technology · 2025Article
- Leveraging ensemble convolutional neural networks and metaheuristic strategies for advanced kidney disease screening and classification.Scientific reports · 2025Article
- Radiation Diagnostics of the Maxillofacial Region and Skeleton Bone Density in the Case of Vitamin D Insufficiency: A Pilot Study.Life (Basel, Switzerland) · 2025Article
- The impact of intravenous iodinated contrast agents on radiotherapy dose calculation and radiobiological effect predictions in central lung cancer.Frontiers in oncology · 2025Article
- Variation in Hounsfield unit calculated using dual-energy computed tomography: comparison of dual-layer, dual-source, and fast kilovoltage switching technique.Radiological physics and technology · 2024Article
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- Determination of acceptable Hounsfield units uncertainties via a sensitivity analysis for an accurate dose calculation in the context of prostate MRI-only radiotherapy.Physical and engineering sciences in medicine · 2023Article
- Assessment of CBCT gray value in different regions-of-interest and fields-of-view compared to Hounsfield unit.Dento maxillo facial radiology · 2023Article
- Deep learning-based diagnosis of osteoblastic bone metastases and bone islands in computed tomograph images: a multicenter diagnostic study.European radiology · 2023Article
- Clinical feasibility of a commercially available MRI-only method for radiotherapy treatment planning of the brain.Journal of applied clinical medical physics · 2023Article
- COVLIAS 1.0Diagnostics (Basel, Switzerland) · 2022Article
- Impact of computed tomography (CT) reconstruction kernels on radiotherapy dose calculation.Journal of applied clinical medical physics · 2020Article
- Degeneration of the Sacroiliac Joint in Hip Osteoarthritis Patients: A Three-Dimensional Image Analysis.Journal of the Belgian Society of Radiology · 2019Article
- Article
- The impact of mass density variations on an electron Monte Carlo algorithm for radiotherapy dose calculations.Physics and imaging in radiation oncology · 2018Article
- Effects of 16-bit CT imaging scanning conditions for metal implants on radiotherapy dose distribution.Oncology letters · 2018Article
- In vivo MRI features of spinal muscles in the ovine model.Journal of orthopaedic translation · 2016Article
- Article
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5 authors.
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Abstract
purposeDetermination of dose error margins in radiation therapy planning due to variations in Hounsfield Units (HU) values dependent on the use of different CT scanning protocols. PATIENTS AND
methodsBased on a series of different CT scanning protocols used in clinical practice, conversion tables for radiation dose calculations were generated and subsequently tested on a phantom. These tables were then used to recalculate the radiation therapy plans of 28 real patients after an incorrect scanning protocol had inadvertently been used for these patients.
resultsDifferent CT parameter settings resulted in errors of HU values of up to 2.6% for densities of <1.1 g/cm(3), but up to 25.6% for densities of >1.1 g/cm(3). The largest errors were associated with changes in the tube voltage. Tests on a virtual water phantom with layers of variable thickness and density revealed a sawtooth-shaped curve for the increase of dose differences from 0.3 to 0.6% and 1.5% at layer thicknesses of 1, 3, and 7 cm, respectively. Use of a beam hardening filter resulted in a reference dose difference of 0.6% in response to a density change of 5%. The recalculation of data from 28 patients who received radiation therapy to the head revealed an overdose of 1.3 ± 0.4% to the bone and 0.7 ± 0.1% to brain tissue. On average, therefore, one monitor unit (range 0-3 MU) per 100 MU more than the correct dose had been given.
conclusionUse of different CT scanning protocols leads to variations of up to 20% in the HU values. This can result in a mean systematic dose error of 1.5%. Specific conversion tables and automatic CT scanning protocol recognition could reduce dose errors of these types.
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