ArticleBMJ (Clinical research ed.)2013
Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England.
Article in BMJ (Clinical research ed.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pre-Existing and Gestational Diabetes and Risk of Maternal Venous Thromboembolism: A Systematic Review and Meta-Analysis of Observational Studies.BJOG : an international journal of obstetrics and gynaecology · 2025Pooled it
- Limitations for health research with restricted data collection from UK primary care.Pharmacoepidemiology and drug safety · 2019Pooled it
- Postpartum venous thromboembolism prophylaxis may cause more harm than benefit: a critical analysis of international guidelines through an evidence-based lens.BJOG : an international journal of obstetrics and gynaecology · 2018Pooled it
- Inpatient activity and sleep following vaginal versus scheduled cesarean delivery using actigraphy: an observational pilot study.International journal of obstetric anesthesia · 2026Article
- SARS-CoV-2 infection in pregnant women and incidence of thromboembolic disease: an analysis of the Covid-19-Related Obstetric and Neonatal Outcome Study (CRONOS) in Germany.Archives of gynecology and obstetrics · 2025Observational
- Inpatient pharmacological thromboprophylaxis in the antepartum period: an argument for risk-based thromboprophylaxis.American journal of obstetrics & gynecology MFM · 2025Review
- Low-molecular-weight heparins utilization in pregnant and postpartum women: a real-world analysis in China (2016-2021).Frontiers in pharmacology · 2025Article
- Peripartum management of the patient taking anticoagulant medications.BJA education · 2025Review
- Efficacy of an enhanced recovery nursing plan as a rooming-in practice for women with preeclampsia post-cesarean section.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Activity Restriction and Hospitalization in Pregnancy: Can Bed-Rest Exercise Prevent Deconditioning? A Narrative Review.International journal of environmental research and public health · 2023Review
- Venous thromboembolism risk score during hospitalization in pregnancy: results of 10694 prospective evaluations in a clinical trial.Clinics (Sao Paulo, Brazil) · 2023Article
- Successful Thrombolytic Therapy Using Ultraslow Low-Dose Infusion During Pregnancy for Mitral Mechanical Valve Thrombosis: A Case Series and Review of the Literature.European journal of case reports in internal medicine · 2023Article
- A Review of Cardiovascular Complications among Pregnant Patients with COVID-19.Reviews in cardiovascular medicine · 2022Review
- Diseases and complications of the puerperium.Deutsches Arzteblatt international · 2021Review
- Article
- Community-based, population-focused preterm birth prevention programs - a review.Archives of gynecology and obstetrics · 2020Review
- COVID-19 coagulopathy in pregnancy: Critical review, preliminary recommendations, and ISTH registry-Communication from the ISTH SSC for Women's Health.Journal of thrombosis and haemostasis : JTH · 2020Review
- COVID-19 Pandemic and Pregnancy in Kidney Disease.Advances in chronic kidney disease · 2020Review
- Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2019Article
- Venous thromboembolism as a cause of severe maternal morbidity and mortality in the United States.Seminars in perinatology · 2019Review
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the potential for preventing venous thromboembolism during and after antepartum hospital admissions in pregnant women.
designCohort study using linked primary (Clinical Practice Research Datalink) and secondary (Hospital Episode Statistics) care records.
settingPrimary and secondary care centres, England.
participants206,785 women aged 15-44 who had one or more pregnancies from 1997 up to 2010.
main outcome measureRisk of first venous thromboembolism in pregnant women admitted to hospital for one or more days for reasons other than delivery or venous thromboembolism. Risk was assessed by calculating the absolute rate of venous thromboembolism and comparing these rates with those observed during follow-up time not associated with hospital admission using a Poisson regression model to estimate incidence rate ratios.
resultsAdmission to hospital in pregnancy was associated with an increased risk of venous thromboembolism (absolute rate 1752/100,000 person years; incidence rate ratio 17.5, 95% confidence interval 7.69 to 40.0) compared with time outside hospital. The rate of venous thromboembolism was also high during the 28 days after discharge (absolute rate 676; 6.27, 3.74 to 10.5). The rate during and after admission combined was highest in the third trimester (961; 5.57, 3.32 to 9.34) and in those aged ≥ 35 years (1756; 21.7, 9.62 to 49.0). While the absolute rate in the combined period was highest for those with three or more days in hospital (1511; 12.2, 6.65 to 22.7), there was also a fourfold increase (558; 4.05, 2.23 to 7.38) in the risk of venous thromboembolism for those admitted to hospital for less than three days.
conclusionThe overall risk of first venous thromboembolism in pregnant women increased during admissions to hospital not related to delivery, and remained significantly higher in the 28 days after discharge. During these periods need for thromboprophylaxis should receive careful consideration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.