Trial reportBMC psychiatry2013
Assessment of quality of life in people with severe and enduring anorexia nervosa: a comparison of generic and specific instruments.
Trial report in BMC psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Specific psychological therapies versus other therapies or no treatment for severe and enduring anorexia nervosa.The Cochrane database of systematic reviews · 2023Pooled it
- The Neuropsychological Profile of Severe and Enduring Anorexia Nervosa: A Systematic Review.Frontiers in psychology · 2021Pooled it
- The current clinical approach to feeding and eating disorders aimed to increase personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Quality of Life and Clinical Impairment in Spanish Adolescent Anorexia Nervosa Patients.European journal of investigation in health, psychology and education · 2024Article
- Inclusion of the severe and enduring anorexia nervosa phenotype in genetics research: a scoping review.Journal of eating disorders · 2024Article
- Validation of the Spanish version of the eating disorders quality of life instrument (EDQOL).Journal of eating disorders · 2023Article
- An Examination of the Relationships between Eating-Disorder Symptoms, Difficulties with Emotion Regulation, and Mental Health in People with Binge Eating Disorder.Behavioral sciences (Basel, Switzerland) · 2023Article
- Explanatory Factors for Disease-Specific Health-Related Quality of Life in Women with Anorexia Nervosa.Journal of clinical medicine · 2021Article
- Effects associated with the use of healthcare for eating disorders by women in the community: a longitudinal cohort study.BMJ open · 2020Article
- Reliability and validity of the Japanese translation of the Eating Disorders Quality of Life (ED-QOL) scale for Japanese healthy female university undergraduate students and patients with eating disorders.BioPsychoSocial medicine · 2020Article
- Relationships between compulsive exercise, quality of life, psychological distress and motivation to change in adults with anorexia nervosa.Journal of eating disorders · 2018Article
- Characterizing severe and enduring anorexia nervosa: An empirical approach.The International journal of eating disorders · 2017Article
- Quantitative and Qualitative Analysis of the Quality of Life of Individuals With Eating Disorders.The primary care companion for CNS disorders · 2015Article
- Resistance to treatment in eating disorders: a critical challenge.BMC psychiatry · 2013Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCriticisms that generic measures of health-related quality of life (HRQoL) are not sensitive to impairment in anorexia nervosa (AN) has spurred the development of disease-specific measures. This study aimed to compare the psychometric properties of a generic to a disease-specific measure of HRQoL.
methods63 participants with AN completed measures of a generic HRQoL (SF-12), disease-specific HRQoL (Eating Disorders Quality of Life Questionnaire; EDQOL), functional impairment (days out of role; DOR; Work and Social Adjustment Scale; WSAS), and eating disorder severity (Eating Disorder Examination; EDE) at baseline, post-treatment, and 6- and 12-months follow-up. Cronbach's α was computed for the SF-12 and EDQOL (internal consistency). Correlations were assessed between SF-12/EDQOL scores and DOR, WSAS, and EDE scores (convergence validity). Three sets of three multiple linear regressions were performed using SF-12 and EDQOL scores as predictors and change in DOR, WSAS, and EDE global scores from baseline to (i) post-treatment, (ii) 6-month follow-up, (iii) and 12-month follow-up as dependent variables (predictive validity and sensitivity).
resultsThe EDQOL displayed stronger internal consistency (α = 0.92) than the SF-12 (α = 0.80). The SF-12 converged more strongly with DOR and the WSAS (r(p) = -0.31 to -0.63 vs. 0.06 to 0.70), while the EDQOL converged more strongly with the EDE (r(p) = -0.01 to 0.48 vs. -0.01 to -0.37). The SF-12 demonstrated stronger predictive validity (β = -0.55 to 0.29) and sensitivity to changes in ED severity (β = -0.47 to 0.32).
conclusionsThe SF-12 is a valid and sensitive measure of HRQoL impairment in patients with AN. While the SF-12 may be preferred in research comparing EDs to other populations, and in research and practice as an indicator of functional impairment; the EDQOL may be preferred by clinicians and researchers interested in HRQoL impairment specifically associated with an ED and as an additional indicator of ED severity.
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