ReviewDiabetes & metabolism journal2013
The Interplay between Autophagy and Aging.
Review in Diabetes & metabolism journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Antiaging agents: safe interventions to slow aging and healthy life span extension.Natural products and bioprospecting · 2022Review
- Acceleration of slow autophagy flux induced by arabinofuranosyl cytidine improves its antileukemic effectiveness in M-NFS-60 cells.Turkish journal of biology = Turk biyoloji dergisi · 2022Article
- Glycans in autophagy, endocytosis and lysosomal functions.Glycoconjugate journal · 2021Review
- Reduced cardiomyocyte NaJournal of cellular physiology · 2019Article
- Evaluation of ATG7 and Light Chain 3 (LC3) Autophagy Genes Expression in AML Patients.Iranian journal of pharmaceutical research : IJPR · 2019Article
- Methods to Determine the Role of Autophagy Proteins in C. elegans Aging.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Ventricular pro-arrhythmic phenotype, arrhythmic substrate, ageing and mitochondrial dysfunction in peroxisome proliferator activated receptor-γ coactivator-1β deficient (Pgc-1βMechanisms of ageing and development · 2018Article
- From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home.Biomedical journal · 2017Review
- Metformin Restores Parkin-Mediated Mitophagy, Suppressed by Cytosolic p53.International journal of molecular sciences · 2016Article
- Successful aging: Advancing the science of physical independence in older adults.Ageing research reviews · 2015Review
- Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling.The Journal of biological chemistry · 2015Article
- Autophagy: a housekeeper in cardiorenal metabolic health and disease.Biochimica et biophysica acta · 2015Review
- Autophagy and Lipid Droplets in the Liver.Annual review of nutrition · 2015Review
- Zinc and autophagy.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2014Review
- Autophagy in the eye: implications for ocular cell health.Experimental eye research · 2014Review
- In search of antiaging modalities: evaluation of mTOR- and ROS/DNA damage-signaling by cytometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2014Review
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous studies have established a link between autophagy and aging; however, the relationship has not been clearly defined. Aging is a very complex process caused by the accumulation of various factors due to the gradual failure of cellular maintenance. Recent studies have shown that autophagy reduces the stress responses induced by starvation, reactive oxygen species, and the accumulation of intracellular proteins and organelles through cytoprotection, clearance of damaged mitochondria, and lysosomal degradation. Here, we summarize our current understanding of the relationship between autophagy and the aging process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.