ReviewJournal of neurogastroenterology and motility2013
Abdominal bloating: pathophysiology and treatment.
Review in Journal of neurogastroenterology and motility, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04507867 (Effect of a Nutritional Support System to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of a Nutritional Support System to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of multistrain probiotics on symptom severity in irritable bowel syndrome: a systematic review and meta-analysis of irritable bowel syndrome-symptom severity score outcomes.European journal of gastroenterology & hepatology · 2026Pooled it
- Efficacy and Safety of Pea Protein and Xyloglucan Versus Simethicone in Functional Abdominal Bloating and Distension.Digestive diseases and sciences · 2024Trial
- Bacillus Subtilis (BG01-4Nutrients · 2023Trial
- Effects of the DASH Diet and Sodium Intake on Bloating: Results From the DASH-Sodium Trial.The American journal of gastroenterology · 2019Trial
- Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial.PloS one · 2015Trial
- The probioticGut microbesTrial
- Agomelatine improves symptom severity and quality of life in diarrhea-predominant irritable bowel syndrome: insights from a randomized controlled clinical trial.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Fructose malabsorption associated with functional abdominal bloating: Case-control study.World journal of gastrointestinal pharmacology and therapeutics · 2026Article
- Association of dietary fat type with abdominal bloating: a case control study.BMC gastroenterology · 2026Article
- Follow-up of bowel endometriosis resections performed using the double circular stapler technique: A decade's experience.PloS one · 2025Observational
- Disclosing the benefits of multi-strain compounds and their health impact mechanisms utilizing intestinal biomimetic technology.Frontiers in microbiology · 2025Article
- [The Relationship of Dysbiosis of Duodenal Microbiome and Functional Dyspepsia].The Korean journal of helicobacter and upper gastrointestinal research · 2024Review
- Functional Abdominal Bloating and Gut Microbiota: An Update.Microorganisms · 2024Review
- Psychometric Evaluation of the Abdominal Bloating Social Support Scale.The Malaysian journal of medical sciences : MJMS · 2024Article
- Effect of Trimebutine and Rifaximin on Breath Hydrogen and Methane by Glucose Breath Test in Patients With Functional Bloating: A Randomized Double-blind Clinical Trial.Journal of neurogastroenterology and motility · 2024Article
- The Disease Spectrum and Natural History of Patients With Abdominal Bloating or Distension: A Longitudinal Study.Journal of neurogastroenterology and motility · 2024Article
- Spot Hydrogen Breath Test for Predicting Response to Low Fermentable Oligo-, Di-, Mono-saccharides, and Polyols Dietary Advice in Patients With Bloating.Journal of neurogastroenterology and motility · 2023Article
- Article
- Association Between Food Intake and Gastrointestinal Symptoms in Patients With Obesity.Gastro hep advances · 2023Article
- A Theory Planned Behaviour of Study on Improving Abdominal Bloating among the Malays Population: A Qualitative Study.The Malaysian journal of medical sciences : MJMS · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abdominal bloating is a very common and troublesome symptom of all ages, but it has not been fully understood to date. Bloating is usually associated with functional gastrointestinal disorders or organic diseases, but it may also appear alone. The pathophysiology of bloating remains ambiguous, although some evidences support the potential mechanisms, including gut hypersensitivity, impaired gas handling, altered gut microbiota, and abnormal abdominal-phrenic reflexes. Owing to the insufficient understanding of these mechanisms, the available therapeutic options are limited. However, medical treatment with some prokinetics, rifaximin, lubiprostone and linaclotide could be considered in the treatment of bloating. In addition, dietary intervention is important in relieving symptom in patients with bloating.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.