ArticleFrontiers in neural circuits2013
Sudden synchrony leaps accompanied by frequency multiplications in neuronal activity.
Article in Frontiers in neural circuits, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Optimal responsiveness and information flow in networks of heterogeneous neurons.Scientific reports · 2021Article
- Neuronal response impedance mechanism implementing cooperative networks with low firing rates and μs precision.Frontiers in neural circuits · 2015Article
- Editorial: Towards an integrated approach to measurement, analysis and modeling of cortical networks.Frontiers in neural circuits · 2015Article
- Broadband macroscopic cortical oscillations emerge from intrinsic neuronal response failures.Frontiers in neural circuits · 2015Article
- A computational paradigm for dynamic logic-gates in neuronal activity.Frontiers in computational neuroscience · 2014Article
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6 authors.
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Abstract
A classical view of neural coding relies on temporal firing synchrony among functional groups of neurons, however, the underlying mechanism remains an enigma. Here we experimentally demonstrate a mechanism where time-lags among neuronal spiking leap from several tens of milliseconds to nearly zero-lag synchrony. It also allows sudden leaps out of synchrony, hence forming short epochs of synchrony. Our results are based on an experimental procedure where conditioned stimulations were enforced on circuits of neurons embedded within a large-scale network of cortical cells in vitro and are corroborated by simulations of neuronal populations. The underlying biological mechanisms are the unavoidable increase of the neuronal response latency to ongoing stimulations and temporal or spatial summation required to generate evoked spikes. These sudden leaps in and out of synchrony may be accompanied by multiplications of the neuronal firing frequency, hence offering reliable information-bearing indicators which may bridge between the two principal neuronal coding paradigms.
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