Evidence map›Paper›PMID 24198518›Full record

ArticleStem cells and cloning : advances and applications2010

Gene transfection in primary stem-like cells of giant cell tumor of bone.

Shalini Singh, Isabella Mak, Patricia Power, Melissa Cunningham, Melissa Cunnigham, Robert Turcotte, Michelle Ghert

Erratum issuedAbstract read
In one paragraph

Article in Stem cells and cloning : advances and applications, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Shalini SinghDepartment of Surgery, McMaster University, Hamilton, Ontario.
Isabella Mak
Patricia Power
Melissa Cunningham
Melissa Cunnigham
Robert Turcotte
Michelle Ghert

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neoplastic stem-like stromal cell of giant cell tumor of bone (GCT) survives for multiple passages in primary culture with a stable phenotype, and exhibits multipotent characteristics. The pathophysiology of this tumor has been studied through the primary culture of these cells. However, successful gene transfer of these cells has not been reported to date. In this short report, we describe the development of the first reported technique that results in efficient gene transfection in primary stem-like cells of GCT.

Indexed as

genegiant cell tumorprimary cellstransfectionTWIST

Identifiers

PMID24198518
PMCPMC3781737

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.