Evidence map›Paper›PMID 24198245›Full record

ArticleNucleic acids research2014

PubChem BioAssay: 2014 update.

Yanli Wang, Tugba Suzek, Jian Zhang, Jiyao Wang, Siqian He, Tiejun Cheng, Benjamin A Shoemaker, Asta Gindulyte, Stephen H Bryant

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed
43.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 281 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Protein-Ligand Docking in the Machine-Learning Era.Molecules (Basel, Switzerland) · 2022
    Review
  17. Article
  18. Curated Data In - TrustworthyAlternatives to laboratory animals : ATLA · 2021
    Review
  19. Review
  20. Article

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yanli WangNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Tugba Suzek
Jian Zhang
Jiyao Wang
Siqian He
Tiejun Cheng
Benjamin A Shoemaker
Asta Gindulyte
Stephen H Bryant
National Institutes of Health · USNational Center for Biotechnology Information · US

Funding

Structural Biology Information ResourcesZIALM000046 · NLM · NATIONAL LIBRARY OF MEDICINE · PI BRYANT, STEPHEN H · 2009 to 2017
$45.4M
Chemical Biology Information ResourcesZIALM100604 · NLM · NATIONAL LIBRARY OF MEDICINE · PI BRYANT, STEPHEN H · 2009 to 2017
$39.6M
Intramural NIH HHS
6 · The paper itself

Abstract

PubChem's BioAssay database (http://pubchem.ncbi.nlm.nih.gov) is a public repository for archiving biological tests of small molecules generated through high-throughput screening experiments, medicinal chemistry studies, chemical biology research and drug discovery programs. In addition, the BioAssay database contains data from high-throughput RNA interference screening aimed at identifying critical genes responsible for a biological process or disease condition. The mission of PubChem is to serve the community by providing free and easy access to all deposited data. To this end, PubChem BioAssay is integrated into the National Center for Biotechnology Information retrieval system, making them searchable by Entrez queries and cross-linked to other biomedical information archived at National Center for Biotechnology Information. Moreover, PubChem BioAssay provides web-based and programmatic tools allowing users to search, access and analyze bioassay test results and metadata. In this work, we provide an update for the PubChem BioAssay resource, such as information content growth, new developments supporting data integration and search, and the recently deployed PubChem Upload to streamline chemical structure and bioassay submissions.

Indexed as

Databases, ChemicalHigh-Throughput Screening AssaysRNA InterferenceDrug DiscoveryGenesHumansInternetProteinsSmall Molecule LibrariesSystems IntegrationProteinsSmall Molecule Libraries

Identifiers

PMID24198245
PMCPMC3965008
OpenAlexW2077004593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.