ArticleTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2014
Cerebral radiation injury and changes in the brain tissues of rat models with glioma.
Article in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 citing papers in PubMed, 3 citations in OpenAlex.
- Magnetic resonance imaging evaluation of brain glioma before postoperative radiotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021Article
- Effect of Low-Dose Gamma Radiation and Lipoic Acid on High- Radiation-Dose Induced Rat Brain Injuries.Dose-response : a publication of International Hormesis SocietyArticle
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4 authors at 2 institutions in 1 country.
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Abstract
Cerebral radiation injury (CRI) is a crucial and common complication of radiotherapy for patients with glioma. In the study, we aimed to investigate the changes in the diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) and the histological changes in the brain tissues of mice models with glioma. After the tumor cell seeding, there was an obvious increase in the proportion of cellular nucleus in the brain tissues of rat models with glioma. There was also an obvious increase in the microvascular density (MVD) in the brain tissues of rat models with glioma. There was a linear correlation between the mean apparent diffusion coefficient value and the proportion of cellular nucleus in the brain tissues of rat models with glioma (P < 0.05). There was also a linear correlation between the maximal relative cerebral volume and MVD count in the brain tissues of rat models with glioma (P < 0.01). Therefore, the changes in the DWI and PWI are related with the histological changes in the brain tissues of glioma, and the finding may help us make a distinction between postoperative recurrent glioma and CRI.
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