Evidence map›Paper›PMID 24197554›Full record

ArticleBrain structure & function2015

Enhanced characterization of the zebrafish brain as revealed by super-resolution track-density imaging.

Jeremy F P Ullmann, Fernando Calamante, Shaun P Collin, David C Reutens, Nyoman D Kurniawan

Abstract read
In one paragraph

Article in Brain structure & function, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeremy F P UllmannCentre for Advanced Imaging, The University of Queensland, Brisbane, QLD, 4072, Australia, j.ullmann@uq.edu.au.
Fernando Calamante
Shaun P Collin
David C Reutens
Nyoman D Kurniawan

Funding

A population-bases atlas of the zebrafish brain for quantitative phenotypic compaR03NS077295 · NINDS · UNIVERSITY OF QUEENSLAND · PI JANKE, ANDREW LINDSAY, KURNIAWAN, NYOMAN DANA · 2011 to 2012
$78k
NINDS NIH HHS R03 NS077295
6 · The paper itself

Abstract

In this study, we explored the use of super-resolution track-density imaging (TDI) for neuroanatomical characterization of the adult zebrafish brain. We compared the quality of image contrast and resolution obtained with T2* magnetic resonance imaging (MRI), diffusion tensor-based imaging (DTI), TDI, and histology. The anatomical structures visualized in 5 μm TDI maps corresponded with histology. Moreover, the super-resolution property and the local-directional information provided by directionally encoded color TDI facilitated delineation of a larger number of brain regions, commissures and small white matter tracks when compared to conventional MRI and DTI. In total, we were able to visualize 17 structures that were previously unidentifiable using MR microimaging, such as the four layers of the optic tectum. This study demonstrates the use of TDI for characterization of the adult zebrafish brain as a pivotal tool for future phenotypic examination of transgenic models of neurological diseases.

Indexed as

Brain MappingDiffusion Tensor ImagingAnimalsAnisotropyBrainImaging, Three-DimensionalNeural PathwaysWhite MatterZebrafish

Identifiers

PMID24197554
PMCPMC8863403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.