ArticleEuropean journal of applied physiology2014
The effect of muscle fatigue on stimulus intensity requirements for central and peripheral fatigue quantification.
Article in European journal of applied physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Innovative Dose-Response Assessment of the Metaboreflex With Indirect Control of Intramuscular Metabolic Perturbation in Humans.Acta physiologica (Oxford, England) · 2026Trial
- Sodium bicarbonate induces alkalosis, but improves high-intensity cycling performance only when participants expect a beneficial effect: a placebo and nocebo study.European journal of applied physiology · 2024Trial
- Acute acetaminophen ingestion improves performance and muscle activation during maximal intermittent knee extensor exercise.European journal of applied physiology · 2018Trial
- Quadriceps Muscle Length Differentially Affects Exercise Capacity, the Torque-Duration Relationship, and Neuromuscular Fatigue.Scandinavian journal of medicine & science in sports · 2026Article
- Neuromuscular contributions to inter-limb quadriceps strength asymmetries across contraction types in healthy adults.European journal of applied physiology · 2026Article
- Oleuropein-based olive leaf extract enhances muscle mitochondrial bioenergetics response to moderate - but not maximal - intensity exercise in humans.The Journal of physiology · 2026Article
- Etiology and recovery of knee extensor muscle fatigue following simulated basketball match-play.Biology of sport · 2025Article
- Immediate but not prolonged effects of submaximal eccentric vs concentric fatiguing protocols on the etiology of hamstrings' motor performance fatigue.European journal of applied physiology · 2024Article
- Acute neuromuscular, cardiovascular, and muscle oxygenation responses to low-intensity aerobic interval exercises with blood flow restriction.Experimental physiology · 2024Article
- β-Alanine Plus Sodium Bicarbonate Co-Supplementation Does Not Decrease Neuromuscular Fatigue in Swimming.International journal of exercise science · 2024Article
- Peripheral muscle function during repeated changes of direction in professional soccer players.European journal of applied physiology · 2022Article
- Immediate voluntary activation deficits following submaximal eccentric contractions of knee extensors are associated with alterations of the sense of movement.Scientific reports · 2022Article
- Perception of effort during an isometric contraction is influenced by prior muscle lengthening or shortening.European journal of applied physiology · 2021Article
- Motor strategy during postural control is not muscle fatigue joint-dependent, but muscle fatigue increases postural asymmetry.PloS one · 2021Article
- Is there an intermuscular relationship in voluntary activation capacities and contractile kinetics?European journal of applied physiology · 2020Article
- Sustained Isometric Wrist Flexion and Extension Maximal Voluntary Contractions Similarly Impair Hand-Tracking Accuracy in Young Adults Using a Wrist Robot.Frontiers in sports and active living · 2020Article
- Maturation-related changes in the development and etiology of neuromuscular fatigue.European journal of applied physiology · 2019Article
- Three weeks of sprint interval training improved high-intensity cycling performance and limited ryanodine receptor modifications in recreationally active human subjects.European journal of applied physiology · 2019Article
- Stretch-shortening cycle exercise produces acute and prolonged impairments on endurance performance: is the peripheral fatigue a single answer?European journal of applied physiology · 2019Article
- Mental fatigue does not alter performance or neuromuscular fatigue development during self-paced exercise in recreationally trained cyclists.European journal of applied physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present study was designed to determine the stimulation intensity necessary for an adequate assessment of central and peripheral components of neuromuscular fatigue of the knee extensors.
methodsThree different stimulation intensities (100, 120 and 150% of the lowest intensity evoking a plateau in M-waves and twitch amplitudes, optimal stimulation intensity, OSI) were used to assess voluntary activation level (VAL) as well as M-wave, twitch and doublet amplitudes before, during and after an incremental isometric exercise performed by 14 (8 men) healthy and physically active volunteers. A visual analog scale was used to evaluate the associated discomfort.
resultsThere was no difference (p > 0.05) in VAL between the three intensities before and after exercise. However, we found that stimulating at 100% OSI may overestimate the extent of peripheral fatigue during exercise, whereas 150% OSI stimulations led to greater discomfort associated with doublet stimulations as well as to an increased antagonist co-activation compared to 100% OSI.
conclusionWe recommend using 120% OSI, as it constitutes a good trade-off between discomfort and reliable measurements.
Indexed as
Identifiers
24197080What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.