ReviewCellular and molecular life sciences : CMLS2014
Mechanisms regulating GABAergic neuron development.
Review in Cellular and molecular life sciences : CMLS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed.
- Article
- [Effect of repeated transcranial magnetic stimulation on excitability of glutaminergic neurons and gamma-aminobutyric neurons in mouse hippocampus].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025Article
- UNC-30/PITX coordinates neurotransmitter identity with postsynaptic GABA receptor clustering.Development (Cambridge, England) · 2024Article
- Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Ocular and neural genes jointly regulate the visuospatial working memory in ADHD children.Behavioral and brain functions : BBF · 2023Article
- Cortical interneuron development is affected in 4H leukodystrophy.Brain : a journal of neurology · 2023Article
- Nonparametric single-cell multiomic characterization of trio relationships between transcription factors, target genes, and cis-regulatory regions.Cell systems · 2022Article
- Prdm12 regulates inhibitory neuron differentiation in mouse embryonal carcinoma cells.Cytotechnology · 2022Article
- FoxO1 Regulates Neuropeptide Y and Pro-opiomelanocortin in the Hypothalamus of Rat Offspring Small for Gestational Age.Reproductive sciences (Thousand Oaks, Calif.) · 2022Article
- Neonatal Oxidative Stress Impairs Cortical Synapse Formation and GABA Homeostasis in Parvalbumin-Expressing Interneurons.Oxidative medicine and cellular longevity · 2022Article
- SOX2 Regulates Neuronal Differentiation of the Suprachiasmatic Nucleus.International journal of molecular sciences · 2021Article
- Article
- Characterization of neurogenic niches in the telencephalon of juvenile and adult sharks.Brain structure & function · 2020Article
- Circuit development in the master clock network of mammals.The European journal of neuroscience · 2020Review
- The Genetic Programs Specifying Kolmer-Agduhr Interneurons.Frontiers in neuroscience · 2020Review
- Cend1, a Story with Many Tales: From Regulation of Cell Cycle Progression/Exit of Neural Stem Cells to Brain Structure and Function.Stem cells international · 2019Review
- Sequential Role of SOXB2 Factors in GABAergic Neuron Specification of the Dorsal Midbrain.Frontiers in molecular neuroscience · 2018Article
- Increased Anxiety-Related Behavior, Impaired Cognitive Function and Cellular Alterations in the Brain of Cend1-deficient Mice.Frontiers in cellular neuroscience · 2018Article
- Distinct Activities of Tfap2A and Tfap2B in the Specification of GABAergic Interneurons in the Developing Cerebellum.Frontiers in molecular neuroscience · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurons using gamma-aminobutyric acid (GABA) as their neurotransmitter are the main inhibitory neurons in the mature central nervous system (CNS) and show great variation in their form and function. GABAergic neurons are produced in all of the main domains of the CNS, where they develop from discrete regions of the neuroepithelium. Here, we review the gene expression and regulatory mechanisms controlling the main steps of GABAergic neuron development: early patterning of the proliferative neuroepithelium, production of postmitotic neural precursors, establishment of their identity and migration. By comparing the molecular regulation of these events across CNS, we broadly identify three regions utilizing distinct molecular toolkits for GABAergic fate determination: telencephalon-anterior diencephalon (DLX2 type), posterior diencephalon-midbrain (GATA2 type) and hindbrain-spinal cord (PTF1A and TAL1 types). Similarities and differences in the molecular regulatory mechanisms reveal the core determinants of a GABAergic neuron as well as provide insights into generation of the vast diversity of these neurons.
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Registered trials
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