Evidence map›Paper›PMID 24196525›Full record

ArticleHeart and vessels2014

Mitral and aortic valve sclerosis/calcification and carotid atherosclerosis: results from 1065 patients.

Andrea Rossi, Pompilio Faggiano, Alexandra E Amado, Mariantonietta Cicoira, Stefano Bonapace, Lorenzo Franceschini, Frank L Dini, Stefano Ghio, Eustachio Agricola, Pier Luigi Temporelli and 1 more

Abstract read
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In one paragraph

Article in Heart and vessels, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Andrea RossiDipartimento di Medicina, Sezione di Cardiologia, University of Verona, Verona, Italy, andrea.rossi@ospedaleuniverona.it.
Pompilio Faggiano
Alexandra E Amado
Mariantonietta Cicoira
Stefano Bonapace
Lorenzo Franceschini
Frank L Dini
Stefano Ghio
Eustachio Agricola
Pier Luigi Temporelli
Corrado Vassanelli
University of Verona · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITFondazione Salvatore Maugeri · ITPoliclinico San Matteo Fondazione · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study assesses whether aortic valve sclerosis (AVS) and mitral annulus calcification (MAC) are associated with carotid artery atherosclerosis, independently of traditional cardiovascular risk factors. A total of 1065 patients underwent both echocardiography and carotid artery ultrasound scanning. AVS and MAC were defined as focal areas of increased echogenicity and thickening of the aortic leaflets or mitral valve annulus. Carotid artery atherosclerosis was defined as presence/absence of any atherosclerotic plaque or presence/absence of plaque >50 %. Of 1065 patients (65 ± 9 years; 38 % female) who comprised the study population, 642 (60 %) had at least one atherosclerotic plaque. AVS, but not mitral valve sclerosis; was associated with the presence of carotid atherosclerosis (odds ratio (OR) 1.9, 95 % confidence interval (CI) 1.2-3.9; P = 0.005) and the degree of carotid atherosclerosis (OR 2.1, 95 % CI 1.2-3.9; P = 0.01) in a multivariate model including age, gender, previous ischemic heart disease, hypertension, dyslipidemia, smoking, diabetes, family cardiovascular history, left ventricular size, mass, and ejection fraction, and left atrial size. AVS is a significant predictor of carotid atherosclerosis, independently of other cardiovascular clinical and echocardiographic risk factors.

Indexed as

Aortic Valve StenosisCalcinosisCarotid Artery DiseasesAgedAortic ValveCarotid ArteriesEchocardiographyFemaleHeart Valve DiseasesHumansMaleMiddle AgedMitral ValvePlaque, AtheroscleroticRetrospective StudiesRisk Factors

Identifiers

PMID24196525
OpenAlexW2070293312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.