ArticleJournal of human genetics2014
Mitochondrial DNA history of Sri Lankan ethnic people: their relations within the island and with the Indian subcontinental populations.
Article in Journal of human genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- West Eurasian mtDNA lineages in India: an insight into the spread of the Dravidian language and the origins of the caste system.Human genetics · 2015Trial
- Nasal Gracilization in Sri Lankan Indigenous Vedda: Phenotypic Plasticity and Evolutionary Continuity.American journal of biological anthropology · 2026Article
- Reference values for maximum oxygen consumption (VOBMJ open respiratory research · 2026Article
- Sri Lankan maternal ancestry reveals early migrations from Africa along the Indian Ocean.PloS one · 2026Article
- Population histories of the Indigenous Adivasi and Sinhalese from Sri Lanka using whole genomes.Current biology : CB · 2025Article
- The maternal ancestry of the Kavaratti islanders and the last glacial maximum aftermath.Molecular genetics and genomics : MGG · 2023Article
- Reconstructing the population history of the Sinhalese, the major ethnic group in Śrī Laṅkā.iScience · 2023Article
- Gene therapy for selected neuromuscular and trinucleotide repeat disorders - An insight to subsume South Asia for multicenter clinical trials.IBRO neuroscience reports · 2023Article
- Article
- Mitochondrial DNA (CA)Genetica · 2022Article
- X-chromosomal STR based genetic polymorphisms and demographic history of Sri Lankan ethnicities and their relationship with global populations.Scientific reports · 2021Article
- Evaluation of non-coding region sequence variants and mitochondrial haplogroups as potential biomarkers of sporadic breast cancer in individuals of Sri Lankan Sinhalese ethnicity.Biomedical reports · 2020Article
- Phenotypic spectrum and genetic heterogeneity of cystic fibrosis in Sri Lanka.BMC medical genetics · 2019Article
- The peopling of Lakshadweep Archipelago.Scientific reports · 2019Article
- Establishment of Reference Norms for Lung Function Parameters of Healthy Sri Lankan Tamils.Pulmonary medicine · 2019Article
- Neolithic phylogenetic continuity inferred from complete mitochondrial DNA sequences in a tribal population of Southern India.Genetica · 2018Article
- Historical Tropical Forest Reliance amongst the Wanniyalaeto (Vedda) of Sri Lanka: an Isotopic Perspective.Human ecology: an interdisciplinary journal · 2018Article
- Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics.Pharmacogenetics and genomics · 2016Article
- Language isolates and their genetic identity: a commentary on mitochondrial DNA history of Sri Lankan ethnic people: their relations within the island and with the Indian subcontinental populations.Journal of human genetics · 2014Article
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6 authors.
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Abstract
Located only a short distance off the southernmost shore of the Greater Indian subcontinent, the island of Sri Lanka has long been inhabited by various ethnic populations. Mainly comprising the Vedda, Sinhalese (Up- and Low-country) and Tamil (Sri Lankan and Indian); their history of settlements on the island and the biological relationships among them have remained obscure. It has been hypothesized that the Vedda was probably the earliest inhabitants of the area, followed by Sinhalese and Tamil from the Indian mainland. This study, in which 271 individuals, representing the Sri Lankan ethnic populations mentioned, were typed for their mitochondrial DNA (mtDNA) hypervariable segment 1 (HVS-1) and part of hypervariable segment 2 (HVS-2), provides implications for their settlement history on the island. From the phylogenetic, principal coordinate and analysis of molecular variance results, the Vedda occupied a position separated from all other ethnic people of the island, who formed relatively close affiliations among themselves, suggesting a separate origin of the former. The haplotypes and analysis of molecular variance revealed that Vedda people's mitochondrial sequences are more related to the Sinhalese and Sri Lankan Tamils' than the Indian Tamils' sequences. MtDNA haplogroup analysis revealed that several West Eurasian haplogroups as well as Indian-specific mtDNA clades were found amongst the Sri Lankan populations. Through a comparison with the mtDNA HVS-1 and part of HVS-2 of Indian database, both Tamils and Sinhalese clusters were affiliated with Indian subcontinent populations than Vedda people who are believed to be the native population of the island of Sri Lanka.
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