Evidence map›Paper›PMID 24196355›Full record

ArticleInternational journal of molecular sciences2013

The anti-fasciolasis properties of silver nanoparticles produced by Trichoderma harzianum and their improvement of the anti-fasciolasis drug triclabendazole.

Youssuf A Gherbawy, Ismail M Shalaby, Mahmoud Syed Abd El-Sadek, Hesham M Elhariry, Banaja A Abdelilah

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 58 citations in OpenAlex.

  1. In Vitro Effects of Vanadate Erbium/Silver Oxide (ErVOVeterinary medicine and science · 2025
    Article
  2. Article
  3. Food and waterborne parasitology · 2024
    Article
  4. Article
  5. The Potential ofNanomaterials (Basel, Switzerland) · 2023
    Review
  6. Review
  7. Article
  8. Frontiers in fungal biology · 2021
    Review
  9. Drug resistance in liver flukes.International journal for parasitology. Drugs and drug resistance · 2020
    Review
  10. Review
  11. Article
  12. Synthesis of Silver Nanoparticles Mediated by Fungi: A Review.Frontiers in bioengineering and biotechnology · 2019
    Review
  13. Molecular characterization ofSaudi journal of biological sciences · 2019
    Article
  14. Iranian journal of parasitology
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Youssuf A GherbawyDepartment of Biological Sciences, Faculty of Science, Taif University, P.O. Box 888, Taif 21974, Saudi Arabia. youssufgherbawy@yahoo.com.
Ismail M Shalaby
Mahmoud Syed Abd El-Sadek
Hesham M Elhariry
Banaja A Abdelilah
Taif University · SAAin Shams University · EGSouth Valley University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, new strains of Fasciola demonstrated drug resistance, which increased the need for new drugs or improvement of the present drugs. Nanotechnology is expected to open some new opportunities to fight and prevent diseases using an atomic scale tailoring of materials. The ability to uncover the structure and function of biosystems at the nanoscale, stimulates research leading to improvement in biology, biotechnology, medicine and healthcare. The size of nanomaterials is similar to that of most biological molecules and structures; therefore, nanomaterials can be useful for both in vivo and in vitro biomedical research and applications. Therefore, this work aimed to isolate fungal strains from Taif soil samples, which have the ability to synthesize silver nanoparticles. The fungus Trichoderma harzianum, when challenged with silver nitrate solution, accumulated silver nanoparticles (AgNBs) on the surface of its cell wall in 72 h. These nanoparticles, dislodged by ultrasonication, showed an absorption peak at 420 nm in a UV-visible spectrum, corresponding to the plasmon resonance of silver nanoparticles. The transmission electron micrographs of dislodged nanoparticles in aqueous solution showed the production of reasonably monodisperse silver nanoparticles (average particle size: 4.66 nm) by the fungus. The percentage of non hatching eggs treated with the Triclabendazole drug was 69.67%, while this percentage increased to 89.67% in combination with drug and AgNPs.

Indexed as

BenzimidazolesDrug CombinationsFascioliasisHumansMetal NanoparticlesNanotechnologyParticle SizeSilverTrichodermaTriclabendazoleBenzimidazolesDrug CombinationsSilverTriclabendazole

Identifiers

PMID24196355
PMCPMC3856041
OpenAlexW2091680347

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.