Evidence map›Paper›PMID 24195702›Full record

ArticleJournal of the International Society of Sports Nutrition2013

Combined effect of branched-chain amino acids and taurine supplementation on delayed onset muscle soreness and muscle damage in high-intensity eccentric exercise.

Song-Gyu Ra, Teruo Miyazaki, Keisuke Ishikura, Hisashi Nagayama, Shoichi Komine, Yoshio Nakata, Seiji Maeda, Yasushi Matsuzaki, Hajime Ohmori

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the International Society of Sports Nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Article
  12. Review
  13. Article
  14. Functional Properties of Meat in Athletes' Performance and Recovery.International journal of environmental research and public health · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Taurine in sports and exercise.Journal of the International Society of Sports Nutrition · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Song-Gyu Ra *Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8574, Japan.
Teruo Miyazaki *Joint Research Center, Tokyo Medical University Ibaraki Medical Center, Ami, Ibaraki 300-0395, Japan.
Keisuke IshikuraSports Research and Development Core, University of Tsukuba, Tsukuba, Ibaraki 305-8574, Japan.
Hisashi NagayamaSchool of Health and Physical Education, University of Tsukuba, Tsukuba, Ibaraki 305-8574, Japan.
Shoichi KomineGraduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8574, Japan.
Yoshio NakataFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8574, Japan.
Seiji MaedaFaculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8574, Japan.
Yasushi MatsuzakiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokyo Medical University Ibaraki Medical Center, Ami, Ibaraki 300-0395, Japan.
Hajime OhmoriFaculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8574, Japan.
University of Tsukuba · JPTokyo Medical University Ibaraki Medical Center · JPJapan Society for the Promotion of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have evaluated the effectiveness of branched-chain amino acid (BCAA) supplementation for preventing delayed onset muscle soreness (DOMS) and muscle damage induced by eccentric exercise, their findings have been inconclusive. Since taurine has anti-inflammatory and anti-oxidative effects, the present study investigated the combined effect of BCAA and taurine on DOMS and muscle damage.

methodsThirty-six untrained male subjects (22.5 ± 3.8 years) were assigned to four groups (placebo + placebo [placebo], BCAA + placebo, placebo + taurine, and BCAA + taurine [combined]) and given a combination of 3.2 g BCAA (or placebo) and 2.0 g taurine (or placebo), three times a day, for two weeks prior to and three days after eccentric elbow flexor exercises. DOMS and muscle damage in the biceps brachii were subjectively and objectively evaluated using the visual analogue scale (VAS), upper arm circumference (CIR), and blood parameters (creatine kinase, lactate dehydrogenase [LDH], aldolase, and 8-hydroxydeoxyguanosine [8-OHdG]).

resultsIn the combined group, VAS and 8-OHdG two days after exercise, CIR two and three days after exercise and LDH from one to three days after exercise were significantly lower than the placebo group. The area under the curve from before exercise to four days later for CIR, LDH, and aldolase was also significantly lower in the combined group than in the placebo group.

conclusionA combination of 3.2 g BCAA and 2.0 g taurine, three times a day, for two weeks prior to and three days after exercise may be a useful nutritional strategy for attenuating exercise-induced DOMS and muscle damage.

Identifiers

PMID24195702
PMCPMC3827986
OpenAlexW2101762028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.