ArticleSocial cognitive and affective neuroscience2014
Memory consolidation of fear conditioning: bi-stable amygdala connectivity with dorsal anterior cingulate and medial prefrontal cortex.
Article in Social cognitive and affective neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A translational perspective on neural circuits of fear extinction: Current promises and challenges.Neurobiology of learning and memory · 2018Pooled it
- White matter tract microstructure of the mPFC-amygdala predicts interindividual differences in placebo response related to treatment in migraine patients.Human brain mapping · 2019Trial
- Nociceptin/orphanin FQ receptor agonism attenuates behavioral and neural responses to conditioned aversive stimuli.Translational psychiatry · 2026Article
- Dynamic representations of valence in anterior cingulate cortex in mice.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Effect of stellate ganglion block on the prevention of posttraumatic stress disorder in patients undergoing emergency ocular trauma surgery: protocol for a randomized, double-blind, placebo-controlled trial.Frontiers in medicine · 2025Article
- State-dependent memory mechanisms insights from neural circuits and clinical implications.Frontiers in cellular neuroscience · 2025Review
- The mind, brain, and body study: A protocol for examining the effects of the gut-brain-immune axis on internalizing symptoms in youth exposed to caregiving-related early adversity.Brain, behavior, & immunity - health · 2024Article
- An externally validated resting-state brain connectivity signature of pain-related learning.Communications biology · 2024Article
- Changes in brain rhythms and connectivity tracking fear acquisition and reversal.Brain structure & function · 2023Article
- Inhibitory circuits in fear memory and fear-related disorders.Frontiers in neural circuits · 2023Review
- Fear Extinction Learning in Posttraumatic Stress Disorder.Current topics in behavioral neurosciences · 2023Article
- Transcranial direct-current stimulation enhances Pavlovian tendencies during intermittent loss of control.Frontiers in psychiatry · 2023Article
- A Critical Period for Prefrontal Network Configurations Underlying Psychiatric Disorders and Addiction.Frontiers in behavioral neuroscience · 2020Article
- Genetic variation in dopamine availability modulates the self-reported level of action control in a sex-dependent manner.Social cognitive and affective neuroscience · 2019Article
- Clinical Therapeutic Strategy and Neuronal Mechanism Underlying Post-Traumatic Stress Disorder (PTSD).International journal of molecular sciences · 2019Review
- Unresolved-disorganized attachment adjusted for a general psychopathology factor associated with atypical amygdala resting-state functional connectivity.European journal of psychotraumatology · 2019Article
- Cortico-limbic connectivity changes following fear extinction and relationships with trait anxiety.Social cognitive and affective neuroscience · 2018Article
- Ramelteon Improves Post-traumatic Stress Disorder-Like Behaviors Exhibited by Fatty Acid-Binding Protein 3 Null Mice.Molecular neurobiology · 2018Article
- Sleep deprivation affects fear memory consolidation: bi-stable amygdala connectivity with insula and ventromedial prefrontal cortex.Social cognitive and affective neuroscience · 2018Article
- Multi-modal neuroimaging of adolescents with non-suicidal self-injury: Amygdala functional connectivity.Journal of affective disorders · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Investigations of fear conditioning in rodents and humans have illuminated the neural mechanisms of fear acquisition and extinction. However, the neural mechanism of memory consolidation of fear conditioning is not well understood. To address this question, we measured brain activity and the changes in functional connectivity following fear acquisition using resting-state functional magnetic resonance imaging. The amygdala-dorsal anterior cingulate cortex (dACC) and hippocampus-insula functional connectivity were enhanced, whereas the amygdala-medial prefrontal cortex (mPFC) functional coupling was decreased during fear memory consolidation. Furthermore, the amygdala-mPFC functional connectivity was negatively correlated with the subjective fear ratings. These findings suggest the amygdala functional connectivity with dACC and mPFC may play an important role in memory consolidation of fear conditioning. The change of amygdala-mPFC functional connectivity could predict the subjective fear. Accordingly, this study provides a new perspective for understanding fear memory consolidation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.