Evidence map›Paper›PMID 24193951›Full record

ReviewArchives of virology2014

Classification of HHV-6A and HHV-6B as distinct viruses.

Dharam Ablashi, Henri Agut, Roberto Alvarez-Lafuente, Duncan A Clark, Stephen Dewhurst, Dario DiLuca, Louis Flamand, Niza Frenkel, Robert Gallo, Ursula A Gompels and 11 more

Open access · greenAbstract readReview
In one paragraph

Review in Archives of virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 183 papers.

0numbers the graph read from it
0cells of the map it votes in
183citing papers in PubMed
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

183 citing papers in PubMed, 352 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

123 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 19 institutions in 11 countries.

Dharam AblashiHHV-6 Foundation, Santa Barbara, USA, Dharam_Ablashi@HHV-6Foundation.org.
Henri Agut
Roberto Alvarez-Lafuente
Duncan A Clark
Stephen Dewhurst
Dario DiLuca
Louis Flamand
Niza Frenkel
Robert Gallo
Ursula A Gompels
Per Höllsberg
Steven Jacobson
Mario Luppi
Paolo Lusso
Mauro Malnati
Peter Medveczky
Yasuko Mori
Philip E Pellett
Joshua C Pritchett
Koichi Yamanishi
Tetsushi Yoshikawa
HHV-6 Foundation · USAarhus University · DKBarts Health NHS Trust · GBFujita Health University · JPHospital Clínico San Carlos · ESKobe University · JPNational Institute of Allergy and Infectious Diseases · USNational Institute of Neurological Disorders and Stroke · USOsaka University · JPPitié-Salpêtrière Hospital · FRTel Aviv University · ILUniversité Laval · CAUniversity of Ferrara · ITUniversity of London · GBUniversity of Maryland, Baltimore · USUniversity of Modena and Reggio Emilia · ITUniversity of Rochester Medical Center · USUniversity of South Florida · USWayne State University · US

Funding

Involvement Of Human Viruses Associated With Chronic Neurologic DiseaseZIANS002817 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI JACOBSON, STEVEN · 2009 to 2025
$26.5M
Translational studies of human viruses and chronic neurologic diseaseZIANS003040 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI JACOBSON, STEVEN · 2009 to 2025
$10.1M
Retrovirus Associated With Chronic Neurologic DiseaseZ01NS002817 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI JACOBSON, STEVEN · 1990 to 2008
$4.0M
Translational studies of human viruses and chronic neurologic disesaeZ01NS003040 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI JACOBSON, STEVEN · 2007 to 2008
$1.7M
Intramural NIH HHS Z01 NS002817Intramural NIH HHS Z01 NS003040
6 · The paper itself

Abstract

Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses (ICTV) classified HHV-6A and HHV-6B as separate viruses. This review outlines several of the documented epidemiological, biological, and immunological distinctions between HHV-6A and HHV-6B, which support the ICTV classification. The utilization of virus-specific clinical and laboratory assays for distinguishing HHV-6A and HHV-6B is now required for further classification. For clarity in biological and clinical distinctions between HHV-6A and HHV-6B, scientists and physicians are herein urged, where possible, to differentiate carefully between HHV-6A and HHV-6B in all future publications.

Indexed as

Genetic VariationHerpesvirus 6, HumanHumansRoseolovirus Infections

Identifiers

PMID24193951
PMCPMC4750402
OpenAlexW1999091319

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.